What's on this Page
What is Sulconazole
Sulconazole is an azole antifungal of the imidazole subgroup. It is used topically for a variety of fungal and yeast infections.
Sulconazole’s mechanism is largely fungistatic, however the in vitro antifungal spectrum is extremely broad.
Sulconazole is structurally related to and similarly effective for tinea infections as other imidazole-derivative azole antifungal agents such as clotrimazole, econazole, and miconazole.
In some studies of tinea pedis, sulconazole demonstrated a greater efficacy and onset of effect compared to miconazole and clotrimazole.
In the management of tinea cruris/corporis, sulconazole 1% cream applied once daily was as effective as twice daily application of clotrimazole 1% cream.
Brand Name
Exelderm
Indications
- Candida albicans
- Candida glabrata
- Candida guilliermondii
- Candida krusei
- Candida parapsilosis
- Candida pseudotropicalis
- Candida tropicalis
- candidiasis
- Epidermophyton floccosum
- Malassezia furfur
- Microsporum audouinii
- Microsporum canis
- Microsporum gypseum
- tinea corporis
- tinea cruris
- tinea pedis
- tinea versicolor
- Trichophyton mentagrophytes
- Trichophyton rubrum
- Trichophyton tonsurans
- Trichophyton violaceum
Side Effects
- erythema
- pruritus
- skin irritation
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- accidental exposure
- azole antifungals hypersensitivity
- breast-feeding
- children
- ocular exposure
- onychomycosis
- ophthalmic administration
- pregnancy
- vaginal administration
Interactions
- Nystatin
Nystatin: (Moderate) The combination of sulconazole and nystatin represents duplication of therapy whenever the drugs are used by similar routes and are usually avoided.