Scorpion Antivenin (Antivenin Centruroides sculpturatus Equine)

What is Scorpion Antivenin (Antivenin Centruroides sculpturatus Equine)

Scorpion antivenin, antivenin Centruroides sculpturatus equine is used to neutralize the toxic effects of Centruroides scorpion stings.

The polyvalent antivenin is derived from the plasma of horses immunized with Centruroides scorpion venom. Individuals sensitive to horse proteins may experience early or delayed hypersensitivity reactions to the antivenin.

Mild scorpion stings are characterized by local pain and usually resolve untreated over hours to days. Severe stings are characterized by neurologic impairment such as uncoordinated neuromotor hyperactivity, oculomotor and visual abnormalities, and respiratory compromise.

Supportive treatment may involve intensive care unit admission, high doses of benzodiazepines, or mechanical ventilation. Infants and children are more likely than adults to experience severe stings and untreated stings can result in hospitalization and be fatal in this population.

Brand Name

Anascorp

Indications

  • Centruroides scorpion sting

Side Effects

  • anaphylactoid reactions
  • ataxia
  • cough
  • diarrhea
  • fatigue
  • fever
  • headache
  • hypoxia
  • lethargy
  • lymphadenopathy
  • myalgia
  • nausea
  • ocular inflammation
  • palpitations
  • pruritus
  • rash
  • rhinorrhea
  • serum sickness
  • vomiting

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • breast-feeding
  • cresol hypersensitivity
  • equine protein hypersensitivity
  • infection
  • pregnancy
  • requires a specialized care setting

Interactions

There are no drug interactions associated with Scorpion Antivenin, Antivenin Centruroides sculpturatus Equine products.

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