Pramoxine

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Pramoxine Brand Names

Campho-Phenique Cold Sore Treatment for Scab Relief | Dermarest Eczema | New-Skin Poison Ivy | Pramox Gel | Prax | Proctofoam | Sarna Sensitive | Tucks | Vagisil Anti-Itch

What is Pramoxine

Pramoxine is a topical local anesthetic agent. While derived from amide local anesthetics, it is chemically distinct.

It is also known by the name pramocaine. It is used for the temporary relief of pain and itching associated with dermatoses; rashes due to poison ivy, poison oak, poison sumac, insect bites; minor burns; anogenital pruritus or irritation; anal fissures; or rectal hemorrhoids.

Pramoxine is not used for bronchoscopy or gastroscopy because it is not sufficiently potent to abolish the gag reflex, and is considered too irritating for use in mucus membranes like the eyes or nose.

This drug was approved by the FDA in 1953.

Indications

  • hemorrhoids
  • mild pain
  • pruritus

For the temporary relief of mild pain and pruritus associated with various skin conditions

Side Effects

  • contact dermatitis
  • skin irritation

Some patients may rarely develop hypersensitivity to topical pramoxine products, such as allergic contact dermatitis; however, since this anesthetic is chemically distinct from ester local anesthetics and amide local anesthetics, it appears less likely to cause cross-sensitive reactions than some other agents.

If the symptom being treated does not subside or if redness, skin irritation, swelling, pain or other symptoms develop or increase, patients should discontinue use.

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • breast-feeding
  • children
  • GI bleeding
  • infants
  • ophthalmic administration
  • pregnancy

Interactions

  • Adapalene; Benzoyl Peroxide
  • Benzocaine
  • Benzocaine; Butamben; Tetracaine
  • Benzoyl Peroxide
  • Benzoyl Peroxide; Clindamycin
  • Benzoyl Peroxide; Erythromycin
  • Benzoyl Peroxide; Sulfur
  • Dibucaine
  • Ethyl Chloride
  • Hydrocortisone; Lidocaine
  • Lidocaine
  • Lidocaine; Prilocaine
  • Lidocaine; Tetracaine
  • Tetracaine

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