Chloroxylenol Glycerin Pramoxine Zinc

Chloroxylenol Glycerin Pramoxine Zinc Brand Names

Chlorpram Z | Zinotic | Zinotic ES

What is Chloroxylenol Glycerin Pramoxine Zinc

Chloroxylenol glycerin pramoxine, zinc otic solutions are used topically in the ear for the treatment of susceptible superficial ear infections of the external auditory canal (otitis externa).

Chloroxylenol is an antiseptic agent; glycerin is a topical skin protectant and penetration enhancer; pramoxine is a topical anesthetic that provides relief of pain and itching; zinc is a mild astringent as well as a protectant that acts as a physical barrier to irritants.


  • otitis externa

For the treatment of otitis externa, including the accompanying pain and itching

Side Effects

  1. skin irritation
  2. xerosis

Hypersensitivity and other adverse reactions to chloroxylenol; pramoxine; zinc otic combinations are rare. Discontinue treatment if signs and symptoms of a local allergic reaction occur.

The following adverse reactions with topical chloroxylenol; glycerin; pramoxine; zinc have been observed: skin irritation (i.e., redness or swelling), pain (i.e., burning or stinging), or dryness (xerosis); avoid use beyond recommended treatment durations.

Monitoring Parameters

  • laboratory monitoring not necessary


  • breast-feeding
  • ophthalmic administration
  • pregnancy
  • tympanic membrane perforation


There are no drug interactions associated with Chloroxylenol Glycerin Pramoxine Zinc products.


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