Nystatin and Triamcinolone

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Nystatin and Triamcinolone Brand Names

Mycogen-II | Mycolog II | Myco-Triacet-II | Mytrex | N.T.A. | Viaderm KC

What is Nystatin and Triamcinolone

Nystatin and triamcinolone are used together in a topical preparation for short-term (i.e., less than 2 weeks) treatment of candidal skin infections.

Nystatin is an antifungal agent and triamcinolone is a corticosteroid used for its antiinflammatory, vasoconstrictive, and antipruritic properties.

Compared to nystatin or triamcinolone alone, the combination has been shown to provide faster and more pronounced clearing of erythema and pruritus, especially in the first few days of treatment.

Nystatin and triamcinolone was approved by the FDA in May 1985.

Indications

  • Candida albicans
  • Candida sp.
  • candidiasis

Side Effects

  1. acneiform rash
  2. contact dermatitis
  3. Cushing’s syndrome
  4. folliculitis
  5. glycosuria
  6. hyperglycemia
  7. hypertrichosis
  8. hypothalamic-pituitary-adrenal (HPA) suppression
  9. increased intracranial pressure
  10. infection
  11. miliaria
  12. pruritus
  13. skin atrophy
  14. skin hypopigmentation
  15. skin irritation
  16. striae
  17. superinfection
  18. xerosis

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • benzyl alcohol hypersensitivity
  • breast-feeding
  • children
  • corticosteroid hypersensitivity
  • Cushing’s syndrome
  • geriatric
  • hypothalamic-pituitary-adrenal (HPA) suppression
  • infants
  • occlusive dressing
  • ocular exposure
  • peripheral vascular disease
  • pregnancy
  • skin abrasion
  • skin atrophy

Interactions

There are no drug interactions associated with Nystatin and Triamcinolone products.

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