Latanoprost

Latanoprost Brand Names- Xalatan | Xelpros

What is Latanoprost

Latanoprost, an analog of prostaglandin F2alpha, is a prodrug used to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Studies have shown that latanoprost administered once daily is at least as effective as timolol in lowering intraocular pressure.

When latanoprost and timolol were used in combination, a complete or almost complete additive effect in reducing intraocular pressure has been observed.

Treatment has been associated with increased pigmentation of the iris, periorbital tissue (eyelid) and eyelashes

Indications

  • glaucoma
  • ocular hypertension

For the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension

Side Effects

  1. angina
  2. arthralgia
  3. back pain
  4. blepharedema
  5. blepharitis
  6. blurred vision
  7. bronchospasm
  8. chest pain (unspecified)
  9. conjunctival hyperemia
  10. conjunctivitis
  11. corneal edema
  12. corneal erosion
  13. dizziness
  14. dyspnea
  15. foreign body sensation
  16. headache
  17. hypertrichosis
  18. infection
  19. influenza
  20. iridal discoloration
  21. iritis
  22. keratitis
  23. lacrimation
  24. macular edema
  25. musculoskeletal pain
  26. myalgia
  27. ocular discharge
  28. ocular inflammation
  29. ocular irritation
  30. ocular pain
  31. ocular pruritus
  32. palpitations
  33. pharyngitis
  34. photophobia
  35. pruritus
  36. rash
  37. skin hyperpigmentation
  38. toxic epidermal necrolysis
  39. uveitis
  40. visual impairment
  41. xerophthalmia

Monitoring Parameters

  • intraocular pressure
  • ophthalmologic exam

Contraindications

  • aphakia
  • breast-feeding
  • children
  • closed-angle glaucoma
  • contact lenses
  • corneal abrasion
  • hepatic disease
  • infants
  • iritis
  • keratitis
  • neonates
  • ocular infection
  • ocular surgery
  • ocular trauma
  • pregnancy
  • renal disease
  • renal failure
  • renal impairment
  • sunlight (UV) exposure
  • uveitis

Interactions

There are no drug interactions associated with Latanoprost products.