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Latanoprost Brand Names- Xalatan | Xelpros
What is Latanoprost
Latanoprost, an analog of prostaglandin F2alpha, is a prodrug used to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Studies have shown that latanoprost administered once daily is at least as effective as timolol in lowering intraocular pressure.
When latanoprost and timolol were used in combination, a complete or almost complete additive effect in reducing intraocular pressure has been observed.
Treatment has been associated with increased pigmentation of the iris, periorbital tissue (eyelid) and eyelashes
Indications
- glaucoma
- ocular hypertension
For the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension
Side Effects
- angina
- arthralgia
- back pain
- blepharedema
- blepharitis
- blurred vision
- bronchospasm
- chest pain (unspecified)
- conjunctival hyperemia
- conjunctivitis
- corneal edema
- corneal erosion
- dizziness
- dyspnea
- foreign body sensation
- headache
- hypertrichosis
- infection
- influenza
- iridal discoloration
- iritis
- keratitis
- lacrimation
- macular edema
- musculoskeletal pain
- myalgia
- ocular discharge
- ocular inflammation
- ocular irritation
- ocular pain
- ocular pruritus
- palpitations
- pharyngitis
- photophobia
- pruritus
- rash
- skin hyperpigmentation
- toxic epidermal necrolysis
- uveitis
- visual impairment
- xerophthalmia
Monitoring Parameters
- intraocular pressure
- ophthalmologic exam
Contraindications
- aphakia
- breast-feeding
- children
- closed-angle glaucoma
- contact lenses
- corneal abrasion
- hepatic disease
- infants
- iritis
- keratitis
- neonates
- ocular infection
- ocular surgery
- ocular trauma
- pregnancy
- renal disease
- renal failure
- renal impairment
- sunlight (UV) exposure
- uveitis
Interactions
There are no drug interactions associated with Latanoprost products.
