Brinzolamide

Sharing is caring!

Brinzolamide Brand Name– Azopt

What is Brinzolamide

Brinzolamide is a carbonic anhydrase inhibitor. It is administered topically to the eye for the treatment of elevated intraocular pressure (IOP) in patients with ocular hypertension or open-angle glaucoma.

By lowering IOP, brinzolamide reduces the risk of nerve damage and visual field loss in patients with pathologic elevations of intraocular pressure.

Brinzolamide reduces intraocular pressure to the same extent as dorzolamide but ocular burning appears to be less with brinzolamide.

Brinzolamide is a sulfonamide derivative and should not be administered to patients with sulfonamide hypersensitivity.

Final FDA approval for brinzolamide (Azopt) was granted in April 1998.

Indications

  • glaucoma
  • ocular hypertension

For the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma

Side Effects

  1. agranulocytosis
  2. alopecia
  3. aplastic anemia
  4. blepharitis
  5. blurred vision
  6. chest pain (unspecified)
  7. conjunctivitis
  8. diarrhea
  9. diplopia
  10. dizziness
  11. dysgeusia
  12. dyspepsia
  13. dyspnea
  14. foreign body sensation
  15. headache
  16. hepatic necrosis
  17. hyperemia
  18. hypertonia
  19. keratitis
  20. keratoconjunctivitis
  21. keratopathy
  22. lacrimation
  23. nausea
  24. ocular irritation
  25. ocular pain
  26. ocular pruritus
  27. pharyngitis
  28. rhinitis
  29. Stevens-Johnson syndrome
  30. toxic epidermal necrolysis
  31. urticaria
  32. xerophthalmia
  33. xerostomia

Monitoring Parameters

  • intraocular pressure

Contraindications

  • breast-feeding
  • children
  • closed-angle glaucoma
  • contact lenses
  • hepatic disease
  • pregnancy
  • renal disease
  • renal impairment
  • sulfonamide hypersensitivity

Interactions

There are no drug interactions associated with Brinzolamide products.

Sharing is caring!

15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856
Scroll to Top