Guaifenesin Brand Names

AllFen | Altarussin | Altorant | Ambi | Amibid LA | Bidex | Cough | Diabetic Tussin EX | Diabetic Tussin Mucus Relief | Drituss G | Duratuss G | ElixSure EX | Fenesin | Ganidin NR | GERI-TUSSIN | Gua SR | Guaidrine G | Guaifenex G | Guaifenex LA | Guiatuss | Humibid | Humibid E | Humibid LA | Iophen-NR | Liquibid | Miltuss EX | Mucinex | Mucinex Children’s | Mucinex Children’s Chest Congestion | Mucinex Children’s Mini-Melts | Mucinex Junior Strength | Muco-Fen | Mucosa | Mucus + Chest Congestion | Mucus ER | Mucus Relief | Mucus Relief Children’s | MucusRelief DM | Naldecon | Organ-1 NR | Organidin NR | Q-Bid LA | Q-Tussin | Respa-GF | Robafen | Robafen Congestion | Robitussin | Robitussin Mucus + Chest Congestion | Ru-Tuss | Scot-Tussin Expectorant | Siltussin DAS | Siltussin Diabetic DAS-Na | Siltussin SA | Touro EX | Xpect

What is Guaifenesin

Guaifenesin is an oral expectorant, which is commonly used to treat cough due to colds and minor upper respiratory infections. Despite its long history of use since the 1950s, the efficacy of guaifenesin has only recently been substantiated.

Guaifenesin is used for dry, nonproductive cough when there is the presence of tenacious mucus and/or mucus plugs. The results of a few studies have favored active treatment with guaifenesin over placebo in treating productive cough due to upper respiratory illness (URI).

In patients with chronic bronchitis, guaifenesin, is not recommended for aiding with cough suppression since studies have shown no benefit in reducing cough.

However, the mucolytic properties of guaifenesin may be independently helpful in clearing mucus, and patients may subjectively report benefit to use.

Guaifenesin is an ingredient contained in many combination non-prescription (over-the-counter or OTC) and prescription cough and cold products.


  • cough
  • infertility

For the treatment of cough associated with colds and minor upper respiratory tract infections and for loosening phlegm and thin bronchial secretions to aid in clearing bronchial passages and making coughs more productive

Side Effects

  1. abdominal pain
  2. diarrhea
  3. dizziness
  4. drowsiness
  5. headache
  6. nausea
  7. nephrolithiasis
  8. rash
  9. vomiting

Monitoring Parameters

  • laboratory monitoring not necessary


  • asthma
  • breast-feeding
  • bronchitis
  • children
  • emphysema
  • fever
  • geriatric
  • heart failure
  • infants
  • pregnancy
  • tobacco smoking


There are no drug interactions associated with Guaifenesin products.

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