Gatifloxacin

Gatifloxacin Brand Names

Tequin | Zymar | Zymaxid

What is Gatifloxacin

Gatifloxacin is an ophthalmic fluoroquinolone antibiotic. It belongs to a group of quinolones known as 8-methoxy fluoroquinolones.

Gatifloxacin is effective against both gram-positive and gram negative bacteria. Compared to other fluoroquinolones, gatifloxacin and other 8-methoxyfluoroquinolones have markedly improved activity against penicillin-susceptible and -resistant pneumococci.

Gatifloxacin ophthalmic solution is indicated for the treatment of bacterial conjunctivitis in adults and pediatric patients.

Indications

  1. Acinetobacter lwoffii
  2. bacterial conjunctivitis
  3. Bacteroides fragilis
  4. Chlamydophila pneumoniae
  5. Citrobacter freundii
  6. Citrobacter koseri
  7. Clostridium perfringens
  8. Corynebacterium propinquum
  9. Enterobacter cloacae
  10. Escherichia coli
  11. Haemophilus influenzae (beta-lactamase negative)
  12. Haemophilus influenzae (beta-lactamase positive)
  13. Haemophilus parainfluenzae
  14. Klebsiella oxytoca
  15. Klebsiella pneumoniae
  16. Legionella pneumophila
  17. Listeria monocytogenes
  18. Moraxella catarrhalis
  19. Morganella morganii
  20. Mycobacterium fortuitum
  21. Mycobacterium marinum
  22. Mycoplasma pneumoniae
  23. Neisseria gonorrhoeae
  24. Neisseria meningitidis
  25. Peptostreptococcus sp.
  26. Proteus mirabilis
  27. Proteus vulgaris
  28. Serratia marcescens
  29. Staphylococcus aureus (MSSA)
  30. Staphylococcus epidermidis
  31. Staphylococcus saprophyticus
  32. Streptococcus agalactiae (group B streptococci)
  33. Streptococcus mitis
  34. Streptococcus oralis
  35. Streptococcus pneumoniae
  36. Streptococcus pyogenes (group A beta-hemolytic streptococci)
  37. Streptococcus sp.
  38. Streptococcus sp. (Group C)
  39. Streptococcus sp. (Group F)
  40. Streptococcus sp. (Group G)
  41. surgical infection prophylaxis
  42. Vibrio cholerae
  43. Viridans streptococci
  44. Yersinia enterocolitica

Side Effects

  1. anaphylactoid reactions
  2. angioedema
  3. blepharitis
  4. blurred vision
  5. conjunctivitis
  6. corneal edema
  7. dysgeusia
  8. dyspnea
  9. headache
  10. keratitis
  11. lacrimation
  12. laryngeal edema
  13. nausea
  14. ocular discharge
  15. ocular hemorrhage
  16. ocular irritation
  17. ocular pain
  18. ocular pruritus
  19. pruritus
  20. rash
  21. Stevens-Johnson syndrome
  22. urticaria
  23. visual impairment
  24. xerophthalmia

Contraindications

  • breast-feeding
  • fungal infection
  • pregnancy
  • quinolone hypersensitivity

Interactions

There are no drug interactions associated with Gatifloxacin products.

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