Cosyntropin Brand Name– Cortrosyn
What is Cosyntropin
Cosyntropin is a parenteral synthetic peptide containing the same first 24 amino acid sequence as natural corticotropin (ACTH).
Cosyntropin is less potent and less allergenic than other exogenous ACTH preparations (see Corticotropin monograph, separate monograph). It is used for diagnostic testing of adrenal function.
Cosyntropin was approved by the FDA in 1970.
Indications
- adrenocortical insufficiency diagnosis
Side Effects
- anaphylactoid reactions
- bradycardia
- hypertension
- peripheral edema
- rash
- sinus tachycardia
Monitoring Parameters
- blood pressure
- heart rate
- serum cortisol
Contraindications
- breast-feeding
- pregnancy
Interactions
- Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
- Aliskiren; Hydrochlorothiazide, HCTZ
- Amiloride
- Amiloride; Hydrochlorothiazide, HCTZ
- Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
- Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
- Atenolol; Chlorthalidone
- Azilsartan; Chlorthalidone
- Benazepril; Hydrochlorothiazide, HCTZ
- Bendroflumethiazide; Nadolol
- Bisoprolol; Hydrochlorothiazide, HCTZ
- Bumetanide
- Candesartan; Hydrochlorothiazide, HCTZ
- Captopril; Hydrochlorothiazide, HCTZ
- Chlorothiazide
- Chlorthalidone
- Chlorthalidone; Clonidine
- Conjugated Estrogens
- Conjugated Estrogens; Bazedoxifene
- Conjugated Estrogens; Medroxyprogesterone
- Cortisone
- Dienogest; Estradiol valerate
- Diethylstilbestrol, DES
- Drospirenone; Estradiol
- Drospirenone; Ethinyl Estradiol
- Drospirenone; Ethinyl Estradiol; Levomefolate
- Enalapril; Hydrochlorothiazide, HCTZ
- Eprosartan; Hydrochlorothiazide, HCTZ
- Esterified Estrogens
- Esterified Estrogens; Methyltestosterone
- Estradiol
- Estradiol Cypionate; Medroxyprogesterone
- Estradiol; Levonorgestrel
- Estradiol; Norethindrone
- Estradiol; Norgestimate
- Estradiol; Progesterone
- Estrogens
- Estropipate
- Ethacrynic Acid
- Ethinyl Estradiol
- Ethinyl Estradiol; Desogestrel
- Ethinyl Estradiol; Ethynodiol Diacetate
- Ethinyl Estradiol; Etonogestrel
- Ethinyl Estradiol; Levonorgestrel
- Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
- Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
- Ethinyl Estradiol; Norelgestromin
- Ethinyl Estradiol; Norethindrone
- Ethinyl Estradiol; Norethindrone Acetate
- Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
- Ethinyl Estradiol; Norethindrone; Ferrous fumarate
- Ethinyl Estradiol; Norgestimate
- Ethinyl Estradiol; Norgestrel
- Fosinopril; Hydrochlorothiazide, HCTZ
- Furosemide
- Hydralazine; Hydrochlorothiazide, HCTZ
- Hydrochlorothiazide, HCTZ
- Hydrochlorothiazide, HCTZ; Irbesartan
- Hydrochlorothiazide, HCTZ; Lisinopril
- Hydrochlorothiazide, HCTZ; Losartan
- Hydrochlorothiazide, HCTZ; Methyldopa
- Hydrochlorothiazide, HCTZ; Metoprolol
- Hydrochlorothiazide, HCTZ; Moexipril
- Hydrochlorothiazide, HCTZ; Olmesartan
- Hydrochlorothiazide, HCTZ; Propranolol
- Hydrochlorothiazide, HCTZ; Quinapril
- Hydrochlorothiazide, HCTZ; Spironolactone
- Hydrochlorothiazide, HCTZ; Telmisartan
- Hydrochlorothiazide, HCTZ; Triamterene
- Hydrochlorothiazide, HCTZ; Valsartan
- Hydrocortisone
- Loop diuretics
- Mestranol; Norethindrone
- Methyclothiazide
- Metolazone
- Segesterone Acetate; Ethinyl Estradiol
- Spironolactone
- Thiazide diuretics
- Torsemide
- Triamterene
