Capsaicin Metaxalone Brand Name– Metaxall CP
What is Capsaicin Metaxalone
Capsaicin metaxalone includes a topical analgesic, capsaicin, and oral central nervous system (CNS) depressant, metaxalone, for the treatment of musculoskeletal pain.
Metaxalone was FDA-approved in August 1962.
Many formulations of capsaicin are available over-the-counter and are used for temporary relief of pain from arthritis, myalgias, arthralgias, and neuralgias.
The most common adverse effects associated with metaxalone and capsaicin are CNS depression- and dermatologic-related with metaxalone and capsaicin, respectively.
Indications
- musculoskeletal pain
For the treatment of musculoskeletal pain associated with acute, painful musculoskeletal conditions, as an adjunct to rest, physical therapy, and other measures
Side Effects
- anaphylactoid reactions
- anxiety
- burns
- contact dermatitis
- cough
- dizziness
- drowsiness
- drug-induced body odor
- dysgeusia
- dyspepsia
- ecchymosis
- edema
- erythema
- headache
- hemolytic anemia
- hyperesthesia
- hypoesthesia
- irritability
- jaundice
- leukopenia
- maculopapular rash
- nasal irritation
- nausea
- paresthesias
- peripheral neuropathy
- pharyngitis
- pruritus
- rash
- serotonin syndrome
- sinusitis
- skin irritation
- sneezing
- throat irritation
- urticaria
- vomiting
- xerosis
Monitoring Parameters
- LFTs
- serum creatinine/BUN
Contraindications
- accidental exposure
- anemia
- breast-feeding
- driving or operating machinery
- geriatric
- heating pad
- hemolytic anemia
- hepatic disease
- hyperglycemia
- infection
- inflammation
- ocular exposure
- pregnancy
- renal disease
- renal failure
- renal impairment
- skin abrasion
- strenuous exercise
- sunlight (UV) exposure
Interactions
- Acetaminophen; Butalbital
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Codeine
- Acetaminophen; Dextromethorphan; Doxylamine
- Acetaminophen; Dichloralphenazone; Isometheptene
- Acetaminophen; Diphenhydramine
- Acetaminophen; Hydrocodone
- Acetaminophen; Oxycodone
- Acetaminophen; Pentazocine
- Acetaminophen; Tramadol
- Acrivastine; Pseudoephedrine
- Alfentanil
- Alprazolam
- Amitriptyline
- Amitriptyline; Chlordiazepoxide
- Amobarbital
- Amoxapine
- Anxiolytics; Sedatives; and Hypnotics
- Apomorphine
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Oxycodone
- Atropine; Difenoxin
- Atropine; Diphenoxylate
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Azelastine
- Azelastine; Fluticasone
- Bacitracin
- Barbiturates
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Belladonna; Opium
- Benzhydrocodone; Acetaminophen
- Benzodiazepines
- Botulinum Toxins
- Brompheniramine
- Brompheniramine; Carbetapentane; Phenylephrine
- Brompheniramine; Dextromethorphan; Guaifenesin
- Brompheniramine; Guaifenesin; Hydrocodone
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Brompheniramine; Pseudoephedrine
- Buprenorphine
- Buprenorphine; Naloxone
- Buspirone
- Butabarbital
- Butorphanol
- Cannabidiol
- Carbetapentane; Chlorpheniramine
- Carbetapentane; Chlorpheniramine; Phenylephrine
- Carbetapentane; Diphenhydramine; Phenylephrine
- Carbetapentane; Guaifenesin
- Carbetapentane; Guaifenesin; Phenylephrine
- Carbetapentane; Phenylephrine
- Carbetapentane; Phenylephrine; Pyrilamine
- Carbetapentane; Pseudoephedrine
- Carbetapentane; Pyrilamine
- Carbidopa; Levodopa; Entacapone
- Carbinoxamine
- Carbinoxamine; Dextromethorphan; Pseudoephedrine
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Carbinoxamine; Phenylephrine
- Carbinoxamine; Pseudoephedrine
- Cenobamate
- Cetirizine
- Cetirizine; Pseudoephedrine
- Chlophedianol; Dexbrompheniramine
- Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
- Chloral Hydrate
- Chlorcyclizine
- Chlordiazepoxide
- Chlordiazepoxide; Clidinium
- Chlorpheniramine
- Chlorpheniramine; Codeine
- Chlorpheniramine; Dextromethorphan
- Chlorpheniramine; Dextromethorphan; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Phenylephrine
- Chlorpheniramine; Pseudoephedrine
- Clemastine
- Clomipramine
- Clonazepam
- Clorazepate
- Clozapine
- Codeine
- Codeine; Guaifenesin
- Codeine; Phenylephrine; Promethazine
- Codeine; Promethazine
- COMT inhibitors
- Cyclizine
- Cyproheptadine
- Desipramine
- Deutetrabenazine
- Dexchlorpheniramine
- Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
- Dexmedetomidine
- Dextromethorphan; Diphenhydramine; Phenylephrine
- Diazepam
- Dihydrocodeine; Guaifenesin; Pseudoephedrine
- Dimenhydrinate
- Diphenhydramine
- Diphenhydramine; Hydrocodone; Phenylephrine
- Diphenhydramine; Ibuprofen
- Diphenhydramine; Naproxen
- Diphenhydramine; Phenylephrine
- Doxepin
- Doxylamine
- Doxylamine; Pyridoxine
- Dronabinol
- Droperidol
- Entacapone
- Esketamine
- Estazolam
- Eszopiclone
- Ethanol
- Fentanyl
- Flurazepam
- food
- Gabapentin
- General anesthetics
- Guaifenesin; Hydrocodone
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Homatropine; Hydrocodone
- Hydrocodone
- Hydrocodone; Ibuprofen
- Hydrocodone; Phenylephrine
- Hydrocodone; Potassium Guaiacolsulfonate
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Hydromorphone
- Hydroxyzine
- Ibuprofen; Oxycodone
- Imipramine
- Lasmiditan
- Lemborexant
- Levocetirizine
- Levorphanol
- Lofexidine
- Lorazepam
- Loxapine
- Lumateperone
- Maprotiline
- Meclizine
- Mepenzolate
- Meperidine
- Meperidine; Promethazine
- Mephobarbital
- Meprobamate
- Methadone
- Methohexital
- Methscopolamine
- Midazolam
- Mirtazapine
- Molindone
- Morphine
- Morphine; Naltrexone
- Nabilone
- Nalbuphine
- Nortriptyline
- Oxazepam
- Oxycodone
- Oxymorphone
- Ozanimod
- Pentazocine
- Pentazocine; Naloxone
- Pentobarbital
- Perphenazine; Amitriptyline
- Phenobarbital
- Phenothiazines
- Pregabalin
- Primidone
- Protriptyline
- Quazepam
- Remifentanil
- Secobarbital
- Sedating H1-blockers
- Sodium Oxybate
- Sufentanil
- Tapentadol
- Temazepam
- Thalidomide
- Thiopental
- Thiothixene
- Tolcapone
- Tramadol
- Trazodone
- Triazolam
- Tricyclic antidepressants
- Trimipramine
- Triprolidine
- Zaleplon
- Ziprasidone
- Zolpidem
