Capsaicin Menthol Methyl Salicylate

Capsaicin Menthol Methyl Salicylate Brand Name– ZIKS Arthritis Pain Relief

What is Capsaicin Menthol Methyl Salicylate

Capsaicin menthol methyl salicylate are used together in an external preparation for the temporary relief of minor aches and pains associated with arthritis, simple backache, strains, bruises, and sprains.

Capsaicin, naturally derived from peppers, acts as a topical analgesic.

Menthol and methyl salicylate are counterirritants.

They stimulate nerve endings in the skin that respond to pain, warmth, and coolness. Menthol is extracted from peppermint oil or prepared synthetically.

When combined, capsaicin, menthol, and methyl salicylate act together to provide a paradoxical pain-relieving effect by producing a sensation that counters a more intense feeling of pain.

Methyl salicylate (wintergreen oil or sweet birch oil) is synthetically prepared by esterification of salicylic acid with methyl alcohol.


  • arthralgia
  • musculoskeletal pain

For the temporary relief of minor musculoskeletal pain and arthralgia

Side Effects

  1. burns
  2. cough
  3. drug-induced body odor
  4. edema
  5. erythema
  6. maculopapular rash
  7. nasal irritation
  8. paresthesias
  9. pruritus
  10. sinusitis
  11. skin irritation
  12. sneezing
  13. throat irritation
  14. xerosis

Monitoring Parameters

  • laboratory monitoring not necessary


  • accidental exposure
  • breast-feeding
  • heating pad
  • hypertension
  • infection
  • inflammation
  • myocardial infarction
  • ocular exposure
  • pregnancy
  • salicylate hypersensitivity
  • strenuous exercise
  • stroke
  • sunlight (UV) exposure


There are no drug interactions associated with Capsaicin Menthol Methyl Salicylate products.


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