Aspirin Carisoprodol

Aspirin Carisoprodol Brand Name– Soma Compound

What is Aspirin Carisoprodol

Aspirin carisoprodol is indicated for use as adjunctive therapy for the relief of pain, spasms, or limited mobility associated with acute, painful musculoskeletal conditions.

Aspirin, a non-narcotic analgesic with anti-inflammatory effects, is combined with carisoprodol, a centrally-acting skeletal muscle relaxant, in an oral tablet formulation.

One of carisoprodol’s metabolites is meprobamate, which is a commercially available anxiolytic agent. It is unclear, however, whether this metabolite is generated in quantities sufficient to produce a clinical effect.

Once in the body, aspirin is hydrolyzed to salicylate, which is also active.

The anti-inflammatory and analgesic effects of aspirin are roughly equivalent to those of many NSAIDs.

Aspirin carisoprodol was approved by the FDA in 1960.

Indications

  • muscle spasm
  • musculoskeletal pain

For the short-term treatment of acute, painful musculoskeletal conditions (e.g., musculoskeletal pain, muscle spasm) as an adjunct to rest, physical therapy, and other measures

Side Effects

  1. abdominal pain
  2. agitation
  3. agranulocytosis
  4. anaphylactic shock
  5. anaphylactoid reactions
  6. angioedema
  7. aplastic anemia
  8. ataxia
  9. bronchospasm
  10. coma
  11. constipation
  12. depression
  13. diaphoresis
  14. diarrhea
  15. diplopia
  16. dizziness
  17. drowsiness
  18. dysarthria
  19. dyspepsia
  20. dysphagia
  21. erythema multiforme
  22. erythema nodosum
  23. esophageal stricture
  24. esophageal ulceration
  25. esophagitis
  26. euphoria
  27. fever
  28. flushing
  29. gastritis
  30. GI bleeding
  31. headache
  32. hemolytic anemia
  33. hyperuricemia
  34. hyperventilation
  35. hypotension
  36. insomnia
  37. leukocytosis
  38. leukopenia
  39. maculopapular rash
  40. metabolic acidosis
  41. nausea
  42. odynophagia
  43. orthostatic hypotension
  44. pancytopenia
  45. peptic ulcer
  46. platelet dysfunction
  47. prolonged bleeding time
  48. pruritus
  49. psychological dependence
  50. pulmonary edema
  51. purpura
  52. pyrosis (heartburn)
  53. rash
  54. renal failure (unspecified)
  55. respiratory depression
  56. Reye’s syndrome
  57. rhinitis
  58. sinus tachycardia
  59. syncope
  60. thrombocytopenia
  61. tinnitus
  62. tremor
  63. urticaria
  64. vertigo
  65. vomiting
  66. withdrawal

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • abrupt discontinuation
  • anemia
  • anticoagulant therapy
  • asthma
  • breast-feeding
  • carbamate hypersensitivity
  • children
  • CNS depression
  • driving or operating machinery
  • G6PD deficiency
  • gastritis
  • geriatric
  • GI bleeding
  • hematological disease
  • hepatic disease
  • infants
  • influenza
  • intramuscular injections
  • labor
  • nasal polyps
  • neonates
  • NSAID hypersensitivity
  • obstetric delivery
  • peptic ulcer disease
  • porphyria
  • pregnancy
  • renal disease
  • renal failure
  • renal impairment
  • Reye’s syndrome
  • salicylate hypersensitivity
  • substance abuse
  • urticaria
  • varicella

Interactions

  • Abciximab
  • Acetaminophen
  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Butalbital
  • Acetaminophen; Butalbital; Caffeine
  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
  • Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
  • Acetaminophen; Codeine
  • Acetaminophen; Dextromethorphan
  • Acetaminophen; Dextromethorphan; Doxylamine
  • Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
  • Acetaminophen; Dextromethorphan; Phenylephrine
  • Acetaminophen; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Dichloralphenazone; Isometheptene
  • Acetaminophen; Diphenhydramine
  • Acetaminophen; Guaifenesin; Phenylephrine
  • Acetaminophen; Hydrocodone
  • Acetaminophen; Oxycodone
  • Acetaminophen; Pentazocine
  • Acetaminophen; Propoxyphene
  • Acetaminophen; Pseudoephedrine
  • Acetaminophen; Tramadol
  • Acetazolamide
  • Acetohexamide
  • Acidifying Agents
  • Acrivastine; Pseudoephedrine
  • Ado-Trastuzumab emtansine
  • Alfentanil
  • Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
  • Aliskiren; Hydrochlorothiazide, HCTZ
  • Alkalinizing Agents
  • Alogliptin
  • Alogliptin; Metformin
  • Alogliptin; Pioglitazone
  • Alpha-glucosidase Inhibitors
  • Alprazolam
  • Amiloride
  • Amiloride; Hydrochlorothiazide, HCTZ
  • Aminoglycosides
  • Amitriptyline
  • Amitriptyline; Chlordiazepoxide
  • Amlodipine; Benazepril
  • Amlodipine; Celecoxib
  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Amobarbital
  • Amoxapine
  • Amoxicillin
  • Amoxicillin; Clarithromycin; Lansoprazole
  • Amoxicillin; Clarithromycin; Omeprazole
  • Amoxicillin; Clavulanic Acid
  • Amphotericin B
  • Amphotericin B cholesteryl sulfate complex (ABCD)
  • Amphotericin B lipid complex (ABLC)
  • Amphotericin B liposomal (LAmB)
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  • Antithrombin III
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  • Apalutamide
  • Apixaban
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  • Ardeparin
  • Ascorbic Acid, Vitamin C
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Citric Acid; Sodium Bicarbonate
  • Aspirin, ASA; Dipyridamole
  • Aspirin, ASA; Omeprazole
  • Aspirin, ASA; Oxycodone
  • Atenolol; Chlorthalidone
  • Atropine; Difenoxin
  • Atropine; Diphenoxylate
  • Atropine; Hyoscyamine; Phenobarbital; Scopolamine
  • Azelastine
  • Azelastine; Fluticasone
  • Azilsartan; Chlorthalidone
  • Bacitracin
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  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Belladonna; Opium
  • Benazepril
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  • Benzhydrocodone; Acetaminophen
  • Benzodiazepines
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  • Bisoprolol; Hydrochlorothiazide, HCTZ
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  • Bortezomib
  • Botulinum Toxins
  • Bromocriptine
  • Brompheniramine
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Dextromethorphan; Guaifenesin
  • Brompheniramine; Guaifenesin; Hydrocodone
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Bumetanide
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  • Buprenorphine; Naloxone
  • Buspirone
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  • Calcium Carbonate
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  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbetapentane; Pyrilamine
  • Carbidopa; Levodopa; Entacapone
  • Carbinoxamine
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Phenylephrine
  • Carbinoxamine; Pseudoephedrine
  • Cefixime
  • Cefotetan
  • Celecoxib
  • Cenobamate
  • Cetirizine
  • Cetirizine; Pseudoephedrine
  • Chlophedianol; Dexbrompheniramine
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chloral Hydrate
  • Chlorcyclizine
  • Chlordiazepoxide
  • Chlordiazepoxide; Clidinium
  • Chlorothiazide
  • Chlorpheniramine
  • Chlorpheniramine; Codeine
  • Chlorpheniramine; Dextromethorphan
  • Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Phenylephrine
  • Chlorpheniramine; Pseudoephedrine
  • Chlorpromazine
  • Chlorpropamide
  • Chlorthalidone
  • Chlorthalidone; Clonidine
  • Cidofovir
  • Cilostazol
  • Cimetidine
  • Citalopram
  • Citric Acid; Potassium Citrate
  • Citric Acid; Potassium Citrate; Sodium Citrate
  • Citric Acid; Sodium Citrate
  • Clemastine
  • Clomipramine
  • Clonazepam
  • Clopidogrel
  • Clorazepate
  • Clozapine
  • Codeine
  • Codeine; Guaifenesin
  • Codeine; Phenylephrine; Promethazine
  • Codeine; Promethazine
  • Colchicine; Probenecid
  • Colistimethate, Colistin, Polymyxin E
  • Collagenase
  • COMT inhibitors
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  • Cyclizine
  • Cyclosporine
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  • Dapagliflozin; Metformin
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  • Deferasirox
  • Defibrotide
  • Delavirdine
  • Desipramine
  • Deutetrabenazine
  • Dexchlorpheniramine
  • Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Dexmedetomidine
  • Dextromethorphan; Diphenhydramine; Phenylephrine
  • Dextromethorphan; Promethazine
  • Diazepam
  • Dichlorphenamide
  • Diclofenac
  • Diclofenac; Misoprostol
  • Dicloxacillin
  • Diflunisal
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Dimenhydrinate
  • Diphenhydramine
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Diphenhydramine; Ibuprofen
  • Diphenhydramine; Naproxen
  • Diphenhydramine; Phenylephrine
  • Dipyridamole
  • Doravirine; Lamivudine; Tenofovir disoproxil fumarate
  • Doxepin
  • Doxylamine
  • Doxylamine; Pyridoxine
  • Dronabinol
  • Droperidol
  • Drotrecogin Alfa
  • Edoxaban
  • Efalizumab
  • Efavirenz
  • Efavirenz; Emtricitabine; Tenofovir
  • Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
  • Empagliflozin
  • Empagliflozin; Linagliptin
  • Empagliflozin; Linagliptin; Metformin
  • Empagliflozin; Metformin
  • Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
  • Emtricitabine; Tenofovir disoproxil fumarate
  • Enalapril, Enalaprilat
  • Enalapril; Felodipine
  • Enalapril; Hydrochlorothiazide, HCTZ
  • Enoxaparin
  • Entacapone
  • Enzalutamide
  • Epoprostenol
  • Eprosartan; Hydrochlorothiazide, HCTZ
  • Eptifibatide
  • Ertugliflozin; Metformin
  • Ertugliflozin; Sitagliptin
  • Escitalopram
  • Esketamine
  • Eslicarbazepine
  • Esomeprazole
  • Esomeprazole; Naproxen
  • Estazolam
  • Eszopiclone
  • Ethacrynic Acid
  • Ethanol
  • Ethotoin
  • Etodolac
  • Famotidine; Ibuprofen
  • Fedratinib
  • Felbamate
  • Fenofibric Acid
  • Fenoprofen
  • Fentanyl
  • Fish Oil, Omega-3 Fatty Acids (Dietary Supplements)
  • Flavocoxid, Flavocoxid; Citrated Zinc Bisglycinate
  • Fluoxetine
  • Fluoxetine; Olanzapine
  • Fluphenazine
  • Flurazepam
  • Flurbiprofen
  • Fluvoxamine
  • Fondaparinux
  • Foscarnet
  • Fosinopril
  • Fosinopril; Hydrochlorothiazide, HCTZ
  • Fosphenytoin
  • Furosemide
  • Gabapentin
  • Gallium Ga 68 Dotatate
  • Garlic, Allium sativum
  • General anesthetics
  • Ginger, Zingiber officinale
  • Ginkgo, Ginkgo biloba
  • Glimepiride
  • Glimepiride; Pioglitazone
  • Glimepiride; Rosiglitazone
  • Glipizide
  • Glipizide; Metformin
  • Glyburide
  • Glyburide; Metformin
  • Green Tea
  • Griseofulvin
  • Guaifenesin; Hydrocodone
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Heparin
  • Homatropine; Hydrocodone
  • Hyaluronidase
  • Hyaluronidase, Recombinant; Immune Globulin
  • Hydralazine; Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ; Irbesartan
  • Hydrochlorothiazide, HCTZ; Lisinopril
  • Hydrochlorothiazide, HCTZ; Losartan
  • Hydrochlorothiazide, HCTZ; Methyldopa
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Moexipril
  • Hydrochlorothiazide, HCTZ; Olmesartan
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Hydrocodone
  • Hydrocodone; Ibuprofen
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Hydromorphone
  • Hydroxyzine
  • Ibritumomab Tiuxetan
  • Ibrutinib
  • Ibuprofen
  • Ibuprofen; Oxycodone
  • Ibuprofen; Pseudoephedrine
  • Iloprost
  • Imipramine
  • Immune Globulin IV, IVIG, IGIV
  • Incretin Mimetics
  • Indapamide
  • Indomethacin
  • Inotersen
  • Insulins
  • Intravenous Lipid Emulsions
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  • Isoniazid, INH; Rifampin
  • Ketoprofen
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  • Lamivudine; Tenofovir Disoproxil Fumarate
  • Lansoprazole; Naproxen
  • Lasmiditan
  • Lemborexant
  • Lesinurad
  • Lesinurad; Allopurinol
  • Levocetirizine
  • Levorphanol
  • Linagliptin
  • Linagliptin; Metformin
  • Lisinopril
  • Lofexidine
  • Loop diuretics
  • Lorazepam
  • Low Molecular Weight Heparins
  • Loxapine
  • Luliconazole
  • Lumacaftor; Ivacaftor
  • Lumateperone
  • Macimorelin
  • Mannitol
  • Maprotiline
  • Measles Virus; Mumps Virus; Rubella Virus; Varicella Virus Vaccine, Live
  • Meclizine
  • Meclofenamate Sodium
  • Mefenamic Acid
  • Meglitinides
  • Meloxicam
  • Mepenzolate
  • Meperidine
  • Meperidine; Promethazine
  • Mephobarbital
  • Meprobamate
  • Mesoridazine
  • Metformin
  • Metformin; Pioglitazone
  • Metformin; Repaglinide
  • Metformin; Rosiglitazone
  • Metformin; Saxagliptin
  • Metformin; Sitagliptin
  • Methadone
  • Methazolamide
  • Methohexital
  • Methotrexate
  • Methscopolamine
  • Methyclothiazide
  • Methylsulfonylmethane, MSM
  • Metoclopramide
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