Amcinonide

Amcinonide Brand Name– Cyclocort

What is Amcinonide

Amcinonide is a topical high-potency synthetic fluorinated corticosteroid. It is used to relieve the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses and psoriasis.

The high potency of amcinonide is advantageous for treating affected areas with thicker skin such as the palms and soles.

Like other high potency topical agents, amcinonide application should be avoided, if possible, on areas of thinner skin, such as the face and intertriginous areas, because of potential toxicities inherent in fluorinated compounds.

Amcinonide was first approved by the FDA in 1979.

Indications & Dosage

  1. alopecia
  2. atopic dermatitis
  3. contact dermatitis
  4. dermatitis
  5. discoid lupus erythematosus
  6. eczema
  7. exfoliative dermatitis
  8. granuloma annulare
  9. keloids
  10. lichen planus
  11. lichen simplex
  12. lichen striatus
  13. necrobiosis lipoidica diabeticorum
  14. pemphigus
  15. pityriasis rosea
  16. pruritus
  17. Rhus dermatitis
  18. sarcoidosis
  19. sunburn
  20. urticaria

Side Effects

  1. acneiform rash
  2. adrenocortical insufficiency
  3. cataracts
  4. contact dermatitis
  5. Cushing’s syndrome
  6. erythema
  7. folliculitis
  8. glycosuria
  9. growth inhibition
  10. headache
  11. hyperglycemia
  12. hypertension
  13. hypertrichosis
  14. hypothalamic-pituitary-adrenal (HPA) suppression
  15. impaired wound healing
  16. increased intracranial pressure
  17. infection
  18. maculopapular rash
  19. miliaria
  20. ocular hypertension
  21. papilledema
  22. pruritus
  23. pseudotumor cerebri
  24. purpura
  25. skin atrophy
  26. skin hypopigmentation
  27. skin irritation
  28. skin ulcer
  29. striae
  30. telangiectasia
  31. tolerance
  32. visual impairment
  33. withdrawal
  34. xerosis

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • acne rosacea
  • acne vulgaris
  • breast-feeding
  • children
  • corticosteroid hypersensitivity
  • Cushing’s syndrome
  • diabetes mellitus
  • fungal infection
  • geriatric
  • growth inhibition
  • herpes infection
  • hypothalamic-pituitary-adrenal (HPA) suppression
  • increased intracranial pressure
  • infants
  • infection
  • measles
  • neonates
  • occlusive dressing
  • ocular exposure
  • ophthalmic administration
  • perioral dermatitis
  • peripheral vascular disease
  • pregnancy
  • skin abrasion
  • skin atrophy
  • varicella
  • viral infection

Interactions

There are no drug interactions associated with Amcinonide products.

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