Aluminum Chloride

Aluminum Chloride Brand Names

Drysol | Hypercare | Xerac AC

What is Aluminum Chloride

Aluminum chloride is an astringent antiperspirant used topically for the management of uncontrollable, excessive perspiration, as in hyperhidrosis.

The prescription products are long-lasting (e.g., for several days) in duration.

Non-prescription antiperspirant products are also available for use.

Aluminum chloride has been used clinically since pre-1938.


  • hyperhidrosis

Side Effects

  • pruritus
  • skin irritation

Adverse effects of topical aluminum chloride application include local skin irritation such as burning, pruritus, or prickly sensation may occur following application.

Incident rates for skin irritation are not available in manufacturer labeling; however, the reactions are thought to be infrequent given the widespread use of these products within marketed antiperspirants.

Monitoring Parameters

  • laboratory monitoring not necessary


  • breast-feeding
  • children
  • infants
  • neonates
  • ocular exposure
  • pregnancy
  • renal disease
  • renal failure
  • skin abrasion


There are no drug interactions associated with Aluminum Chloride products.


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