Acetylcholine Chloride

Acetylcholine Chloride Brand Name– Miochol-E

What is Acetylcholine Chloride

Acetylcholine chloride is a direct-acting parasympathomimetic ophthalmic agent used to produce miosis during ophthalmic surgery.

It should be administered only in a 1% solution by instillation intraocularly into the anterior chamber of the eye; miosis occurs promptly and lasts for approximately 10 minutes.

This drug was approved by the FDA in 1966.

Indications

  • miosis induction
  • ocular surgery

For miosis induction in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment ocular surgery where rapid miosis may be required

Side Effects

  1. bradycardia
  2. bronchospasm
  3. corneal degeneration
  4. corneal edema
  5. corneal opacification
  6. diaphoresis
  7. dyspnea
  8. flushing
  9. headache
  10. hypotension
  11. optic atrophy

Monitoring Parameters

  • ophthalmologic exam

Contraindications

  • breast-feeding
  • children
  • infants
  • iritis
  • neonates
  • pregnancy

Interactions

  • Ambenonium Chloride
  • Amoxapine
  • Anticholinergics
  • Atropine
  • Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Atropine; Difenoxin
  • Atropine; Diphenoxylate
  • Atropine; Edrophonium
  • Atropine; Hyoscyamine; Phenobarbital; Scopolamine
  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Belladonna; Opium
  • Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Benztropine
  • Chlordiazepoxide; Clidinium
  • Cholinesterase inhibitors
  • Dicyclomine
  • Disopyramide
  • Donepezil
  • Donepezil; Memantine
  • Edrophonium
  • Flavoxate
  • Galantamine
  • Glycopyrrolate
  • Glycopyrrolate; Formoterol
  • Homatropine; Hydrocodone
  • Hyoscyamine
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
  • Indacaterol; Glycopyrrolate
  • Maprotiline
  • Mepenzolate
  • Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
  • Methscopolamine
  • Neostigmine
  • Oxybutynin
  • Physostigmine
  • Propantheline
  • Pyridostigmine
  • Rivastigmine
  • Scopolamine
  • Tacrine
  • Tricyclic antidepressants
  • Trihexyphenidyl
  • Trospium
15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856