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Acetaminophen Chlorpheniramine Dextromethorphan Pseudoephedrine Brand Names
Alka-Seltzer Plus Cold and Cough | Comtrex Nighttime Cold and Cough | Contact Severe Cold and Flu | Genacol | Robitussin Flu | Theraflu Severe Cold and Cough | Triaminic Flu, Cough and Fever | Tylenol Children’s Plus Cold and Cough | Tylenol Children’s Plus Flu | Tylenol Cold Day/Night Pack | Tylenol Cold Nighttime | Vicks Formula 44M
What is Acetaminophen Chlorpheniramine Dextromethorphan Pseudoephedrine
Acetaminophen Chlorpheniramine Dextromethorphan Pseudoephedrine is a non-prescription combination product used for the temporary relief of common cold or flu symptoms including cough, fever, headache, minor aches and pain, nasal and sinus congestion, rhinorrhea, sneezing, and sore throat.
Some products are also indicated for the treatment of allergic rhinitis and other upper respiratory allergies.
Acetaminophen possesses analgesic and antipyretic activity similar to aspirin; however, acetaminophen has no peripheral anti-inflammatory activity or effects on platelet function.
Acetaminophen is the preferred analgesic/antipyretic for patients in whom aspirin is contraindicated (e.g., those who have a history of gastric ulcer or a coagulation disorder). In addition, acetaminophen has been recommended by the American Lung Association as the first line treatment for aches and pains associated with the flu.
Chlorpheniramine is a first generation H-1-antagonist commonly used for treating symptoms related to histamine release such as rhinorrhea and sneezing. In contrast to first generation antihistamines from the ethanolamine class, such as diphenhydramine, chlorpheniramine is less sedating and has less anticholinergic effects.
Dextromethorphan is a cough suppressant related to the opiate agonists; however, it does not exhibit typical opiate agonist characteristics. The only morphine-like characteristic dextromethorphan retains is its antitussive property.
Pseudoephedrine is a sympathomimetic amine used as a decongestant to decrease nasal and sinus congestion. Acetaminophen; chlorpheniramine; dextromethorphan; pseudoephedrine combination products are available for adults and children under many brand names.
Indications
- allergic rhinitis
- common cold
- cough
- fever
- headache
- mild pain
- nasal congestion
- pharyngitis
- rhinorrhea
- sneezing
Side Effects
- abdominal pain
- acute generalized exanthematous pustulosis (AGEP)
- agranulocytosis
- anaphylactic shock
- anaphylactoid reactions
- angina
- angioedema
- anorexia
- anxiety
- aplastic anemia
- arrhythmia exacerbation
- ataxia
- AV block
- bleeding
- blurred vision
- bradycardia
- colitis
- confusion
- constipation
- contact dermatitis
- dizziness
- drowsiness
- dysarthria
- dysuria
- elevated hepatic enzymes
- encephalopathy
- erythema
- excitability
- exfoliative dermatitis
- fever
- GI bleeding
- hallucinations
- headache
- heart failure
- hemolysis
- hemolytic anemia
- hepatic necrosis
- hypertension
- hypoprothrombinemia
- hypotension
- impaired cognition
- insomnia
- interstitial nephritis
- irritability
- jaundice
- lethargy
- maculopapular rash
- methemoglobinemia
- mydriasis
- myocardial infarction
- myocarditis
- nasal dryness
- nausea
- ocular hypertension
- pallor
- palpitations
- pancytopenia
- photophobia
- premature ventricular contractions (PVCs)
- pruritus
- psychosis
- purpura
- rash
- renal failure (unspecified)
- renal papillary necrosis
- renal tubular necrosis
- restlessness
- seizures
- serotonin syndrome
- sinus tachycardia
- stroke
- supraventricular tachycardia (SVT)
- thrombocytopenia
- thrombocytosis
- toxic epidermal necrolysis
- urinary retention
- urticaria
- vomiting
- weakness
- xerophthalmia
- xerostomia
Monitoring Parameters
- LFTs
- serum creatinine/BUN: in chronic use or acute toxicity
Contraindications
- acute myocardial infarction
- alcoholism
- anemia
- angina
- anticholinergic medications
- arteriosclerosis
- asthma
- AV block
- bladder obstruction
- bone marrow suppression
- bradycardia
- breast-feeding
- bronchitis
- bundle-branch block
- cardiac arrhythmias
- cardiac disease
- cardiomyopathy
- children
- chronic obstructive pulmonary disease (COPD)
- closed-angle glaucoma
- contact lenses
- coronary artery disease
- diabetes mellitus
- driving or operating machinery
- emphysema
- G6PD deficiency
- geriatric
- GI obstruction
- head trauma
- heart failure
- hepatic disease
- hepatitis
- hypertension
- hyperthyroidism
- ileus
- immunosuppression
- increased intracranial pressure
- increased intraocular pressure
- infants
- infection
- labor
- MAOI therapy
- myocardial infarction
- neonates
- neutropenia
- obstetric delivery
- peptic ulcer disease
- peripheral vascular disease
- phenylketonuria
- pregnancy
- prostatic hypertrophy
- pyloric stenosis
- renal disease
- renal failure
- renal impairment
- status asthmaticus
- tachycardia
- thyroid disease
- thyrotoxicosis
- tobacco smoking
- urinary retention
- ventricular tachycardia
Interactions
- Abacavir; Lamivudine, 3TC; Zidovudine, ZDV
- Abiraterone
- Acarbose
- Acebutolol
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Codeine
- Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
- Acetaminophen; Dextromethorphan; Phenylephrine
- Acetaminophen; Dichloralphenazone; Isometheptene
- Acetaminophen; Guaifenesin; Phenylephrine
- Acetaminophen; Hydrocodone
- Acetaminophen; Oxycodone
- Acetaminophen; Pentazocine
- Acetaminophen; Propoxyphene
- Acetaminophen; Tramadol
- Acetazolamide
- Aclidinium; Formoterol
- Albiglutide
- Albuterol
- Albuterol; Ipratropium
- Alfentanil
- Aliskiren; Amlodipine
- Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
- Aliskiren; Hydrochlorothiazide, HCTZ
- Alkalinizing Agents
- Alogliptin; Metformin
- Alogliptin; Pioglitazone
- Alosetron
- Alpha-blockers
- Alpha-glucosidase Inhibitors
- Aluminum Hydroxide
- Aluminum Hydroxide; Magnesium Carbonate
- Aluminum Hydroxide; Magnesium Hydroxide
- Aluminum Hydroxide; Magnesium Hydroxide; Simethicone
- Aluminum Hydroxide; Magnesium Trisilicate
- Amantadine
- Ambenonium Chloride
- Amikacin
- Amiloride; Hydrochlorothiazide, HCTZ
- Aminoglycosides
- Amiodarone
- Amlodipine
- Amlodipine; Atorvastatin
- Amlodipine; Benazepril
- Amlodipine; Celecoxib
- Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
- Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
- Amlodipine; Olmesartan
- Amlodipine; Telmisartan
- Amlodipine; Valsartan
- Ammonium Chloride
- Amobarbital
- Amoxapine
- Amphetamine
- Amphetamine; Dextroamphetamine
- Amphetamine; Dextroamphetamine Salts
- Angiotensin II receptor antagonists
- Angiotensin-converting enzyme inhibitors
- Antacids
- Anticholinergics
- Apomorphine
- Aprepitant, Fosaprepitant
- Arformoterol
- Artemether; Lumefantrine
- Articaine; Epinephrine
- Asenapine
- Aspirin, ASA
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Aspirin, ASA; Dipyridamole
- Aspirin, ASA; Omeprazole
- Aspirin, ASA; Oxycodone
- Aspirin, ASA; Pravastatin
- Atazanavir; Cobicistat
- Atenolol
- Atenolol; Chlorthalidone
- Atomoxetine
- Atropine
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Atropine; Difenoxin
- Atropine; Diphenoxylate
- Atropine; Edrophonium
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Azelastine
- Azelastine; Fluticasone
- Azilsartan; Chlorthalidone
- Baclofen
- Barbiturates
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Belladonna; Opium
- Benazepril
- Benazepril; Hydrochlorothiazide, HCTZ
- Bendroflumethiazide; Nadolol
- Benzhydrocodone; Acetaminophen
- Benzodiazepines
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Benzphetamine
- Beta-blockers
- Betaxolol
- Bethanechol
- Bismuth Subsalicylate
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Bisoprolol
- Bisoprolol; Hydrochlorothiazide, HCTZ
- Boceprevir
- Bosentan
- Bretylium
- Brimonidine; Timolol
- Bromocriptine
- Brompheniramine; Carbetapentane; Phenylephrine
- Brompheniramine; Guaifenesin; Hydrocodone
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Budesonide; Formoterol
- Bumetanide
- Bupivacaine
- Bupivacaine Liposomal
- Bupivacaine; Lidocaine
- Buprenorphine
- Buprenorphine; Naloxone
- Bupropion
- Bupropion; Naltrexone
- Buspirone
- Busulfan
- Butabarbital
- Butorphanol
- Caffeine
- Caffeine; Ergotamine
- Calcium Carbonate
- Calcium Carbonate; Magnesium Hydroxide
- Calcium Carbonate; Risedronate
- Calcium Carbonate; Simethicone
- Calcium-channel blockers
- Canagliflozin
- Canagliflozin; Metformin
- Candesartan; Hydrochlorothiazide, HCTZ
- Cannabidiol
- Capsaicin; Metaxalone
- Captopril
- Captopril; Hydrochlorothiazide, HCTZ
- Carbamazepine
- Carbetapentane; Chlorpheniramine
- Carbetapentane; Chlorpheniramine; Phenylephrine
- Carbetapentane; Diphenhydramine; Phenylephrine
- Carbetapentane; Guaifenesin
- Carbetapentane; Guaifenesin; Phenylephrine
- Carbetapentane; Phenylephrine
- Carbetapentane; Phenylephrine; Pyrilamine
- Carbetapentane; Pseudoephedrine
- Carbetapentane; Pyrilamine
- Carbidopa; Levodopa; Entacapone
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Carbinoxamine; Phenylephrine
- Cardiac glycosides
- Carisoprodol
- Carteolol
- Carvedilol
- Celecoxib
- Cenobamate
- Cetirizine
- Cetirizine; Pseudoephedrine
- Charcoal
- Chlophedianol; Guaifenesin; Phenylephrine
- Chloroprocaine
- Chlorothiazide
- Chlorpheniramine; Codeine
- Chlorpheniramine; Dextromethorphan; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Phenylephrine
- Chlorpromazine
- Chlorthalidone
- Chlorthalidone; Clonidine
- Chlorzoxazone
- Cholestyramine
- Choline Salicylate; Magnesium Salicylate
- Cinacalcet
- Citalopram
- Clevidipine
- Clobazam
- Clonidine
- Clozapine
- Cobicistat
- Cocaine
- Codeine
- Codeine; Guaifenesin
- Codeine; Phenylephrine; Promethazine
- Codeine; Promethazine
- Colchicine
- Colchicine; Probenecid
- COMT inhibitors
- Cyclobenzaprine
- Dacomitinib
- Dantrolene
- Dapagliflozin
- Dapagliflozin; Metformin
- Dapagliflozin; Saxagliptin
- Dapsone
- Daratumumab; Hyaluronidase
- Darifenacin
- Darunavir; Cobicistat
- Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
- Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
- Delavirdine
- Desloratadine
- Desloratadine; Pseudoephedrine
- Desvenlafaxine
- Deutetrabenazine
- Dexmedetomidine
- Dextroamphetamine
- Dextromethorphan; Diphenhydramine; Phenylephrine
- Dextromethorphan; Guaifenesin; Phenylephrine
- Dextromethorphan; Promethazine
- Diflunisal
- Digitoxin
- Digoxin
- Dihydrocodeine; Guaifenesin; Pseudoephedrine
- Dihydroergotamine
- Diltiazem
- Dipeptidyl Peptidase-4 Inhibitors
- Diphenhydramine; Hydrocodone; Phenylephrine
- Diphenhydramine; Phenylephrine
- Disopyramide
- Donepezil
- Donepezil; Memantine
- Dopamine
- Dorzolamide; Timolol
- Doxorubicin
- Dronabinol
- Dronedarone
- Droperidol
- Drospirenone; Ethinyl Estradiol
- Drospirenone; Ethinyl Estradiol; Levomefolate
- Droxidopa
- Dulaglutide
- Duloxetine
- Dutasteride; Tamsulosin
- Dyphylline
- Dyphylline; Guaifenesin
- Efavirenz
- Efavirenz; Emtricitabine; Tenofovir
- Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
- Eliglustat
- Eltrombopag
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
- Empagliflozin
- Empagliflozin; Linagliptin
- Empagliflozin; Linagliptin; Metformin
- Empagliflozin; Metformin
- Enalapril, Enalaprilat
- Enalapril; Felodipine
- Enalapril; Hydrochlorothiazide, HCTZ
- Entacapone
- Ephedrine
- Epoprostenol
- Eprosartan; Hydrochlorothiazide, HCTZ
- Ergoloid Mesylates
- Ergonovine
- Ergot alkaloids
- Ergotamine
- Ertugliflozin
- Ertugliflozin; Metformin
- Ertugliflozin; Sitagliptin
- Escitalopram
- Esketamine
- Esmolol
- Eszopiclone
- Ethacrynic Acid
- Ethanol
- Ethinyl Estradiol
- Ethinyl Estradiol; Desogestrel
- Ethinyl Estradiol; Ethynodiol Diacetate
- Ethinyl Estradiol; Etonogestrel
- Ethinyl Estradiol; Levonorgestrel
- Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
- Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
- Ethinyl Estradiol; Norelgestromin
- Ethinyl Estradiol; Norethindrone
- Ethinyl Estradiol; Norethindrone Acetate
- Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
- Ethinyl Estradiol; Norethindrone; Ferrous fumarate
- Ethinyl Estradiol; Norgestimate
- Ethinyl Estradiol; Norgestrel
- Etomidate
- Exenatide
- Ezogabine
- Fedratinib
- Felodipine
- Fentanyl
- Flibanserin
- Fluoxetine
- Fluoxetine; Olanzapine
- Fluphenazine
- Fluticasone; Salmeterol
- Fluticasone; Umeclidinium; Vilanterol
- Fluticasone; Vilanterol
- Fluvoxamine
- Formoterol
- Formoterol; Mometasone
- Fosinopril
- Fosinopril; Hydrochlorothiazide, HCTZ
- Fospropofol
- Furosemide
- Gabapentin
- Galantamine
- Gentamicin
- Ginger, Zingiber officinale
- Givosiran
- Glimepiride; Pioglitazone
- Glimepiride; Rosiglitazone
- Glipizide; Metformin
- Glyburide; Metformin
- Glycopyrrolate; Formoterol
- grapefruit juice
- Green Tea
- Guaifenesin; Hydrocodone
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Guaifenesin; Phenylephrine
- Guanabenz
- Halogenated Anesthetics
- Haloperidol
- Heparin
- Homatropine; Hydrocodone
- Hyaluronidase
- Hyaluronidase, Recombinant; Immune Globulin
- Hydantoins
- Hydralazine; Hydrochlorothiazide, HCTZ
- Hydrochlorothiazide, HCTZ
- Hydrochlorothiazide, HCTZ; Irbesartan
- Hydrochlorothiazide, HCTZ; Lisinopril
- Hydrochlorothiazide, HCTZ; Losartan
- Hydrochlorothiazide, HCTZ; Methyldopa
- Hydrochlorothiazide, HCTZ; Metoprolol
- Hydrochlorothiazide, HCTZ; Moexipril
- Hydrochlorothiazide, HCTZ; Olmesartan
- Hydrochlorothiazide, HCTZ; Propranolol
- Hydrochlorothiazide, HCTZ; Quinapril
- Hydrochlorothiazide, HCTZ; Spironolactone
- Hydrochlorothiazide, HCTZ; Telmisartan
- Hydrochlorothiazide, HCTZ; Triamterene
- Hydrochlorothiazide, HCTZ; Valsartan
- Hydrocodone
- Hydrocodone; Ibuprofen
- Hydrocodone; Phenylephrine
- Hydrocodone; Potassium Guaiacolsulfonate
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Hydromorphone
- Hydroxyprogesterone
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Ibuprofen; Oxycodone
- Iloperidone
- Iloprost
- Imatinib
- Incretin Mimetics
- Indacaterol
- Indacaterol; Glycopyrrolate
- Indapamide
- Insulin Degludec; Liraglutide
- Insulin Glargine; Lixisenatide
- Insulins
- Iobenguane I 131
- Isavuconazonium
- Isocarboxazid
- Isoniazid, INH
- Isoniazid, INH; Pyrazinamide, PZA; Rifampin
- Isoniazid, INH; Rifampin
- Isradipine
- Kanamycin
- Ketamine
- Labetalol
- Lamivudine, 3TC; Zidovudine, ZDV
- Lamotrigine
- Lanthanum Carbonate
- Lasmiditan
- Lemborexant
- Levalbuterol
- Levobetaxolol
- Levobunolol
- Levocetirizine
- Levomethadyl
- Levomilnacipran
- Levorphanol
- Levothyroxine
- Levothyroxine; Liothyronine (Porcine)
- Levothyroxine; Liothyronine (Synthetic)
- Lidocaine
- Lidocaine; Prilocaine
- Linagliptin; Metformin
- Linezolid
- Liothyronine
- Liraglutide
- Lisinopril
- Lithium
- Lixisenatide
- Lofexidine
- Lomitapide
- Loop diuretics
- Loperamide
- Loperamide; Simethicone
- Lopinavir; Ritonavir
- Loratadine
- Loratadine; Pseudoephedrine
- Lorcaserin
- Loxapine
- Lumateperone
- Lurasidone
- Macitentan
- Magnesium Salicylate
- Magnesium Salts
- Maprotiline
- Mecamylamine
- Meclizine
- Meglitinides
- Melatonin
- Memantine
- Meperidine
- Meperidine; Promethazine
- Mephobarbital
- Mepivacaine
- Mepivacaine; Levonordefrin
- Meprobamate
- Metaproterenol
- Metaxalone
- Metformin
- Metformin; Pioglitazone
- Metformin; Repaglinide
- Metformin; Rosiglitazone
- Metformin; Saxagliptin
- Metformin; Sitagliptin
- Methadone
- Methamphetamine
- Methazolamide
- Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
- Methocarbamol
- Methohexital
- Methyclothiazide
- Methyldopa
- Methylene Blue
- Methylergonovine
- Methysergide
- Metoclopramide
- Metolazone
- Metoprolol
- Metyrapone
- Metyrosine
- Midodrine
- Miglitol
- Milnacipran
- Minocycline
- Mipomersen
- Mirabegron
- Mirtazapine
- Mitotane
- Moexipril
- Molindone
- Monoamine oxidase inhibitors
- Morphine
- Morphine; Naltrexone
- Nabilone
- Nadolol
- Nalbuphine
- Nebivolol
- Nebivolol; Valsartan
- Nefazodone
- Nicardipine
- Nicotine
- Nifedipine
- Nimodipine
- Nisoldipine
- Nitrates
- Norepinephrine
- Olanzapine
- Ombitasvir; Paritaprevir; Ritonavir
- Omeprazole; Amoxicillin; Rifabutin
- Omeprazole; Sodium Bicarbonate
- Opiate Agonists
- Oritavancin
- Orphenadrine
- Oxycodone
- Oxymorphone
- Ozanimod
- Paliperidone
- Panobinostat
- Paromomycin
- Paroxetine
- Pazopanib
- Peginterferon Alfa-2b
- Penbutolol
- Penicillin G Benzathine; Penicillin G Procaine
- Penicillin G Procaine
- Pentazocine
- Pentazocine; Naloxone
- Pentobarbital
- Perampanel
- Pergolide
- Perindopril
- Perindopril; Amlodipine
- Perphenazine
- Perphenazine; Amitriptyline
- Phenelzine
- Phenobarbital
- Phenylephrine
- Phenylephrine; Promethazine
- Pimozide
- Pindolol
- Pioglitazone
- Pirbuterol
- Pitolisant
- Plazomicin
- Pneumococcal Vaccine, Polyvalent
- Posaconazole
- Potassium-sparing diuretics
- Pramipexole
- Pramlintide
- Pregabalin
- Prilocaine
- Prilocaine; Epinephrine
- Primidone
- Procarbazine
- Prochlorperazine
- Promethazine
- Propafenone
- Propofol
- Propoxyphene
- Propranolol
- Quetiapine
- Quinapril
- Quinine
- Racepinephrine
- Ramelteon
- Ramipril
- Rasagiline
- Remifentanil
- Reserpine
- Rifabutin
- Rifampin
- Riociguat
- Risperidone
- Ritonavir
- Rituximab; Hyaluronidase
- Rivastigmine
- Rolapitant
- Ropinirole
- Ropivacaine
- Rosiglitazone
- Safinamide
- Salmeterol
- Salsalate
- Secobarbital
- Segesterone Acetate; Ethinyl Estradiol
- Selegiline
- Selexipag
- Semaglutide
- Serotonin-Receptor Agonists
- Sertraline
- SGLT2 Inhibitors
- Sibutramine
- Sincalide
- Sodium Bicarbonate
- Sodium Iodide
- Solifenacin
- Solriamfetol
- Sotalol
- St. John’s Wort, Hypericum perforatum
- Streptomycin
- Sufentanil
- Sulfinpyrazone
- Sulfonylureas
- Suvorexant
- Tacrine
- Tamsulosin
- Tapentadol
- Tasimelteon
- Tedizolid
- Telaprevir
- Telotristat Ethyl
- Terbinafine
- Terbutaline
- Tetracaine
- Thalidomide
- Theophylline, Aminophylline
- Thiazide diuretics
- Thiazolidinediones
- Thiopental
- Thioridazine
- Thiothixene
- Thyroid hormones
- Timolol
- Tizanidine
- tobacco
- Tobramycin
- Tocilizumab
- Tolcapone
- Torsemide
- Tramadol
- Trandolapril
- Trandolapril; Verapamil
- Tranylcypromine
- Trastuzumab; Hyaluronidase
- Trazodone
- Treprostinil
- Tricyclic antidepressants
- Trifluoperazine
- Trimethobenzamide
- Trimetrexate
- Trospium
- Umeclidinium; Vilanterol
- Vasodilators
- Vasopressors
- Vemurafenib
- Venlafaxine
- Verapamil
- Vigabatrin
- Vilazodone
- Vortioxetine
- Warfarin
- Yohimbine
- Zaleplon
- Ziconotide
- Zidovudine, ZDV
- Ziprasidone
- Zolmitriptan
- Zolpidem
