What is Sacituzumab Govitecan Sacituzumab govitecan is an antibody-drug conjugate composed of a humanized monoclonal antibody (sacituzumab) which binds to the trophoblast cell-surface antigen-2 (Trop-2) covalently linked to SN-38, a topoisomerase I inhibitor. It is approved for the treatment of patients with metastatic triple-negative breast cancer who have received at least 2 prior therapies for …
What is Saccharomyces boulardii The yeast species Saccharomyces boulardii is a different species from the Brewer’s yeast species of S. cerevisiae or S. carlsbergensis (also known as S. pastorianus). This yeast is non-pathogenic in most persons, is not a normal inhabitant of the human bowel microflora, and is found naturally on the skin of certain fruits, such as lychee fruit and …
What is S adenosyl L methionine SAM e S-adenosyl-L-methionine (SAM-e) is a naturally occurring molecule that is endogenous to humans; it is present in almost every tissue and fluid in the body. Synonyms for SAM-e include ademetionine, AdoMet, and S-adenosylmethionine. SAM-e is important in a variety of biochemical reactions involving enzymatic transmethylation. The endogenous donation …
What is Ustekinumab Ubrogepant is an oral calcitonin gene-related peptide (CGRP) receptor antagonist indicated for the acute treatment of migraine with or without aura. Brand Name Stelara Indications & Dosage Crohn’s disease psoriasis psoriatic arthritis ulcerative colitis Side Effects abdominal pain acne vulgaris anaphylactic shock angioedema antibody formation arthralgia asthenia back pain candidiasis dental caries …
What is Ursodeoxycholic Acid and Ursodiol Ursodeoxycholic acid, ursodiol is an oral, naturally occurring bile acid agent. Ursodiol is FDA-approved to solubilize radiolucent (cholesterol) gallstones, prevent gallstone formation in obese patients experiencing rapid weight loss, and for the treatment of patients with primary biliary cirrhosis. Brand Name Actigall Urso 250 Urso Forte Indications biliary cirrhosis …
What is Urokinase Urokinase is an enzyme produced by the kidney. Tissue cultures of human kidney cells are used to produce the drug. Urokinase is a parenteral thrombolytic agent that is only indicated for lysis of pulmonary emboli. More improvement on pulmonary angiography, lung perfusion scanning, and hemodynamic measurements within 24 hours occurred with urokinase …
What is Urofollitropin Urofollitropin is a parenteral, human derived urinary gonadotropin formulation used in infertility treatments. The key differences in human-derived FSH (i.e., urofollitropin) and genetically engineered FSH (i.e., r-FSH) are product sources and cost. Urofollitropin treatments are highly purified follitropins extracted from the urine of postmenopausal women. Urofollitropin contains primarily follicle stimulating hormone (FSH). …