What is Secukinumab Secukinumab is a subcutaneously administered human IgG1 monoclonal antibody that selectively binds to the interleukin-17A (IL-17A) cytokine, inhibiting its interaction with the IL-17A receptor. Maintenance dosing is given once monthly. Secukinumab is useful in a variety of inflammatory disorders. Elevated concentrations of IL-17A are found in psoriatic plaques; secukinumab is approved for …
What is Secretin Synthetic human or porcine secretin is a peptide hormone with amino acid sequences identical to naturally occurring secretin. Secretin is indicated for the diagnosis of exocrine pancreas dysfunction or gastrinoma and for identifying the ampulla of Vater and accessory papilla during endoscopic retrograde cholangiopancreatography (ERCP). Brand Names ChiRhoStim SecreFlo Indications endoscopic retrograde …
What is Secobarbital Secobarbital is a short-acting oral barbiturate similar to pentobarbital. The parenteral and rectal formulations are no longer available in the US. It is rarely used in the short-term treatment of insomnia for periods of up to 2 weeks. Preoperatively, secobarbital is used to relieve anxiety and induce sedation. Compared with other barbiturates, …
What is Secnidazole Secnidazole is an oral nitroimidazole antimicrobial indicated for the treatment of bacterial vaginosis in adult women. Secnidazole is approved as single-dose therapy, which was found to be at least as effective as a 7-day course of metronidazole for bacterial vaginosis. In a double-dummy, double-blind, noninferiority study (n = 577), therapeutic success, a …
What is Sebelipase alfa Sebelipase alfa is an intravenous therapy that provides a recombinant form of human lysosomal acid lipase (rhLAL) protein in patients with lysosomal acid lipase (LAL) deficiency. LAL deficiency, also known as Wolman disease and cholesteryl ester storage disease (CESD), is an autosomal recessive lysosomal storage disorder that results in a marked …
What is Scorpion Antivenin (Antivenin Centruroides sculpturatus Equine) Scorpion antivenin, antivenin Centruroides sculpturatus equine is used to neutralize the toxic effects of Centruroides scorpion stings. The polyvalent antivenin is derived from the plasma of horses immunized with Centruroides scorpion venom. Individuals sensitive to horse proteins may experience early or delayed hypersensitivity reactions to the antivenin. Mild scorpion …
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What is Scopolamine Scopolamine, also known as l-hyoscine, is a naturally occurring tertiary antimuscarinic. It is one of the major active alkaloids found in belladonna leaf. Compared with atropine, scopolamine is more potent in its anticholinergic effects on the iris; ciliary body; and salivary, bronchial, and sweat glands. Like atropine, it is considered highly anticholinergic …