What is Ziconotide Ziconotide (Prialt, also known as SNX 1111) is an intrathecally infused synthetic conopeptide derived from the venom of the piscivorous marine snail, Conus magus. Ziconotide is a calcium channel blocker specific to the neuronal calcium channels that regulate synaptic transmission in nociceptive neurons. The non-opiate analgesic is effective for the treatment of severe, …
What is Zanubrutinib Zanubrutinib is a Bruton tyrosine kinase (BTK) inhibitor approved for the treatment of adult patients with mantle cell lymphoma who have received at least 1 prior therapy. It was granted an accelerated approval for use in these patients. Fatal and serious bleeding events have been reported with zanubrutinib therapy, including intracranial bleeding …
What is Zanamivir Zanamivir is a neuraminidase inhibitor antiviral agent that is most commonly administered via oral inhalation and indicated for the treatment of uncomplicated influenza A and B infection in patients 7 years and older and for seasonal influenza prophylaxis in patients 5 years and older. Brand Name Relenza Indications & Dosage avian influenza …
What is Zaleplon Zaleplon is a short-acting, non-benzodiazepine sedative-hypnotic. It belongs to a new class of drugs known as pyrazolopyrimidines. Zaleplon possesses anticonvulsant, anxiolytic, hypnotic, and myorelaxant properties. It has been shown to decrease the time to sleep onset for up to 35 days in clinical trials without tolerance and has minimal withdrawal-emergent adverse effects. …
What is Zalcitabine ddC Zalcitabine (dideoxycytidine, ddC) is an antiretroviral nucleoside reverse transcriptase inhibitor (NRTI). In June 1992, it became the third agent to be approved by the FDA for the treatment of HIV infection. However, because monotherapy with zalcitabine has been shown to be inferior to monotherapy with zidovudine (ZDV), zalcitabine was approved for …
What is Zafirlukast Zafirlukast is an oral leukotriene receptor antagonist for the treatment of asthma. Leukotriene receptor antagonists primarily help to control the inflammatory process of asthma, thus helping to prevent asthma symptoms. Zafirlukast has been effective in controlling persistent asthma symptoms in adults and children >= 5 years of age as monotherapy or in …
What is Suvorexant Suvorexant is an oral orexin receptor antagonist indicated for the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance in adults, including patients with Alzheimer’s disease who have insomnia. Suvorexant alters the signaling of neurotransmitters called orexins, which are responsible for regulating the sleep-wake cycle. Similar to other hypnotics, …