What is Trastuzumab Indications breast cancer gastric cancer For the treatment of patients with HER2-positive breast cancer Side Effects abdominal pain acne vulgaris acute respiratory distress syndrome (ARDS) anaphylactic shock anaphylactoid reactions anemia anemia angioedema anorexia antibody formation arthralgia asthenia back pain bone pain cardiomyopathy chills chills constipation cough depression diarrhea dizziness dysgeusia dyspepsia dysphagia …
What is Tranylcypromine Tranylcypromine is an oral antidepressant of the monoamine oxidase inhibitor (MAOI) class. Due to the dietary restrictions required for MAOI use, as well as their side effect profile and the potential for serious drug-drug and drug-food interactions, MAOIs are primarily considered an option for major depressive disorder (MDD) that is refractory to …
What is Tranexamic Acid Tranexamic acid is an oral and injectable antifibrinolytic agent indicated for short-term use to reduce or prevent hemorrhage and reduce the need for replacement therapy during and after tooth extraction in patients with hemophilia and for the treatment of cyclic heavy menstrual bleeding. Tranexamic acid may increase the risk of thromboembolic …
What is Trandolapril and Verapamil combination medicine Trandolapril, an angiotensin converting enzyme inhibitor, and verapamil, a calcium-channel blocker are used in combination as second-line treatment for hypertension. The drugs have complimentary mechanisms of action which decrease peripheral resistance and lower blood pressure. The combination of oral verapamil and trandolapril demonstrates greater antihypertensive and antiproteinuric effects …
What is Trandolapril Trandolapril is an oral, non-sulfhydryl-containing angiotensin converting enzyme inhibitor (ACEI). It is a prodrug for trandolaprilat which is about 8 times as potent as trandolapril in inhibiting ACE. Trandolapril is structurally similar to enalapril and both require hydrolysis for activity. Because of the pharmacokinetics of the active metabolite, trandolaprilat, trandolapril can be …
What is Trametinib Trametinib is a mitogen-activated extracellular signal-regulated kinase (MEK)1 and MEK2 inhibitor. It inhibits cell growth in BRAF V600 mutation-positive tumors by blocking MEK1 and MEK2 which are proteins activated in the BRAF pathway. Using an FDA-approved test, confirm the presence of the BRAF V600 mutation in tumor specimens prior to initiation of …
What is Tramadol Tramadol is a centrally-acting analgesic with a unique, dual mechanism of action. It is a mu-opioid receptor agonist and a weak inhibitor of norepinephrine and serotonin reuptake. Tramadol exists as a racemic mixture of the trans isomer. Important differences in binding, activity, and metabolism are associated with the two enantiomers. Tramadol is a synthetic …