Crizotinib Brand Name– XALKORI What is Crizotinib Crizotinib is an oral inhibitor of receptor tyrosine kinases, including anaplastic lymphoma kinase (ALK) and ROS1. It is indicated for the treatment of patients with metastatic non-small cell lung cancer that is ALK-positive or ROS1-positive. Monitor ECGs and electrolytes in patients at increased risk for QT prolongation; an …
Crizanlizumab Brand Name– ADAKVEO What is Crizanlizumab Crizanlizumab is an intravenous selectin blocker approved to reduce the frequency of vasoocclusive crises (VOC) in patients with sickle cell disease. Crizanlizumab is the first targeted therapy approved for sickle cell disease. Approval was based on results of the SUSTAIN trial (n = 198), in which the median …
Crisaborole Brand Name– EUCRISA What is Crisaborole Crisaborole is a phosphodiesterase 4 (PDE-4) inhibitor indicated for the topical treatment of mild to moderate atopic dermatitis in adult and pediatric patients 3 months of age and older. Because crisaborole is administered topically, it avoids the gastrointestinal side effects that are associated with apremilast, an orally administered …
Creatine monophosphate – Interesting Facts Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? In summary, because creatine has a completely different chemical structure, it is not an anabolic steroid. Does creatine cause kidney damage/renal dysfunction? Does creatine cause hair loss / baldness? Does creatine lead to dehydration and muscle …
Cranberry Vaccinium macrocarpon Ait Brand Names AZO Cranberry | Ellura | TheraCran | TheraCran HP | TheraCran HP for Kids | TheraCran One What is Cranberry Vaccinium macrocarpon Ait The American cranberry, Vaccinium macrocarpon Ait. is commonly marketed in the US as a sweetened and diluted beverage known as cranberry juice cocktail. The applicable part of the cranberry plant for medical use …
Cosyntropin Brand Name– Cortrosyn What is Cosyntropin Cosyntropin is a parenteral synthetic peptide containing the same first 24 amino acid sequence as natural corticotropin (ACTH). Cosyntropin is less potent and less allergenic than other exogenous ACTH preparations (see Corticotropin monograph, separate monograph). It is used for diagnostic testing of adrenal function. Cosyntropin was approved by …
Cortisone Brand Name– Cortone What is Cortisone Cortisone is an endogenous corticosteroid hormone secreted by the adrenal cortex. Unlike most of the corticosteroids, cortisone exhibits significant mineralocorticoid as well as glucocorticoid properties and is used clinically as replacement therapy in patients with adrenocortical insufficiency. Cortisone has about 80% of the anti-inflammatory and sodium-retaining potency of …