Who is credited with the early descriptions of spondyloarthropathies?
In 1691, the Irish physician Bernard Connor described a skeleton with ankylosing spondylitis. In 1818, the English physician Benjamin Brodie provided the first clinical description of a patient with ankylosing spondylitis and iritis. In the late 1890s, the Russian physician Vladimir von Bechterew, the German–Russian physician Adolf Strumpell, and the French physician Pierre Marie described the clinical features of ankylosing spondylitis before the development of severe deformities. In the early 1900s, the German physician Hans Reiter and the French physicians Noel Fiessinger and Emile Leroy described the clinical characteristics of reactive arthritis. The association with the class I gene, HLA-B27 , is credited to the Americans Lee Schlosstein, Rodney Bluestone, and Paul Terasaki, and the English persons Derrick Brewerton, David James, Maeve Caffrey, and Anne Nicholls.