Who is credited with the early descriptions of scleroderma?
- c. 400 bc —Hippocrates described “persons in whom the skin is stretched, parched, and hard, the disease terminates without sweats.”
- 1842—English physician W.D. Chowne described a child with clinical features.
- 1846—English physician James Startin described an adult with clinical features.
- 1860—French clinician Elie Gintrac coined the term sclerodermie.
- 1862—Maurice Raynaud described the vasospastic phenomenon of painful, cold-induced acrocyanosis.
- 1964—Richard Winterbauer, while a medical student, described the CRST syndrome of calcinosis, Raynaud phenomenon, sclerodactyly, and telangiectasia. The E for esophageal dysmotility was added subsequently (CR E ST).
