Who is credited with the early descriptions of scleroderma

Who is credited with the early descriptions of scleroderma?

  • c. 400 bc —Hippocrates described “persons in whom the skin is stretched, parched, and hard, the disease terminates without sweats.”
  • 1842—English physician W.D. Chowne described a child with clinical features.
  • 1846—English physician James Startin described an adult with clinical features.
  • 1860—French clinician Elie Gintrac coined the term sclerodermie.
  • 1862—Maurice Raynaud described the vasospastic phenomenon of painful, cold-induced acrocyanosis.
  • 1964—Richard Winterbauer, while a medical student, described the CRST syndrome of calcinosis, Raynaud phenomenon, sclerodactyly, and telangiectasia. The E for esophageal dysmotility was added subsequently (CR ST).
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