Risk factors for scleroderma renal crisis

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What are some risk factors for scleroderma renal crisis?

• Early diffuse scleroderma (first 1–4 years after diagnosis).

• Tendon friction rubs.

• Corticosteroid (prednisone > 20 mg/day or prolonged low dose) or cyclosporine use.

• Anti-RNA polymerase III antibody (50%–60%).

Patients with risk factors for SRC should receive counseling regarding routine home blood pressure monitoring (daily or every other day) and be monitored closely with frequent follow-up evaluations and laboratory assessments for microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction.

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