Who is at risk for Sjogrens Syndrome?
Primary SS affects 0.1% to 4% of the population depending on criteria used. It typically affects females between ages 30 and 50 years (female: male = 9:1). It is infrequently seen in children.
Symptoms progress relatively slowly and there is frequently a delay of 5 to 10 years between symptom onset and diagnosis. Secondary SS occurs in up to 15% to 20% of patients with RA and to a lesser extent in other rheumatic diseases.