What is a common complication of neonates born to mothers with myotonic muscular dystrophy?
Some newborns who have inherited the myotonic dystrophy gene from their mothers experience profound weakness, with respiratory failure and bulbar insufficiency requiring endotracheal intubation and mechanical ventilation.
The mortality rate may be as high as 30% to 40%. Should the neonate survive, the weakness resolves spontaneously.
The occurrence of the neonatal syndrome has no effect on the severity of the adult expression of the disease.