What are the two types of myasthenia that may affect the newborn or young infant?
- Transient neonatal myasthenia gravis . Affected neonates are born to mothers with autoimmune myasthenia gravis. Because of transplacental transfer of maternal antiacetylcholine (ACh) receptor antibodies, newborns experience transient weakness and hypotonia, which may be severe and life threatening.
- Nonautoimmune congenital myasthenia syndromes