Significance of increased FDG uptake in the thyroid gland

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What is the significance of increased FDG uptake in the thyroid gland?

Focal FDG uptake in the thyroid gland is generally considered as suspicious for thyroid malignancy until proven otherwise and requires further evaluation with thyroid ultrasonography or tissue sampling. This is in contradistinction to diffuse FDG uptake in the thyroid gland, which may be a normal finding when mild, or due to thyroiditis or Graves’ disease when moderate or marked.

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