What is the significance of increased FDG uptake in the bowel?
Focal FDG uptake in the bowel is generally considered as suspicious for malignancy until proven otherwise and requires further evaluation such as with computed tomography (CT), magnetic resonance imaging (MRI), fluoroscopy, or endoscopy with tissue sampling. Diffuse FDG uptake in the bowel is often physiologic, whereas segmental FDG uptake may be physiologic or inflammatory in nature.