Significance of increased renal echogenicity on Ultrasound

What is the significance of increased renal echogenicity on Ultrasound?

When the right kidney is more echogenic than the normal liver and the left kidney is isoechoic or more echogenic than the normal spleen, the kidneys can be characterized as being abnormally echogenic.

Increased renal echogenicity is an indication of parenchymal disease but is nonspecific for the type of parenchymal disease, which may include acute or chronic glomerulonephritis, acute interstitial nephritis, diabetes mellitus, systemic lupus erythematosus, HIV nephropathy, and amyloidosis.

Percutaneous renal biopsy is therefore frequently required for a definitive diagnosis.

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