Radiographic evaluation in suspected multiple myeloma
If the diagnosis of multiple myeloma is suspected, what radiographic evaluation should be performed?
A skeletal survey is usually obtained. Approximately 75% of patients with multiple myeloma have positive radiographic findings with characteristic “punched-out” osteolytic lesions that have discrete margins and uniform size.
Multiple compression fractures can also be seen. MRI is very sensitive for detecting the presence of bone marrow lesions and may help in determining tumor extent.
FDG PET/CT may also be useful to diagnose, stage, and monitor therapy of multiple myeloma.