Post Kidney transplant malignancies

Post Kidney transplant malignancies

1. The chronic exposure to immunosuppressive agents increases the long-term risk of many malignancies, particularly when compared with the general population.

2. Lymphoproliferative disorders are the most common malignancies complicating organ transplantation, excluding nonmelanoma skin cancer and in situ cervical cancer.

3. The clinical presentation of posttransplant lymphoproliferative disorder is protean. Most patients present with nonspecific complaints, including fatigue, weight loss, and fever.

4. Squamous cell carcinoma occurs 65 to 250 times more frequently in the transplant population than in the general population.

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