What is the natural history of Osteoarthritis?
It is likely that the cartilage changes of OA are asymptomatic for years. Despite this, OA progresses with time in most individuals. The rate of progression can be variable, and once symptomatic, the disease may seem to progress quickly. There may be rare individuals in whom the disease may remain stable or even improve somewhat. Nevertheless, OA can lead to severe limitations in motion and eventual disability. Limitation in usual activities was noted by 60% to 80% of patients who reported having OA according to the National Health Interview Survey.