Most important myopathies due to point mutations in tRNA genes of mitochondrial DNA

What are the most important myopathies due to point mutations in tRNA genes of mitochondrial DNA?

• Myoclonic epilepsy with ragged red fibers (MERRF)

• Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS)

• Some myopathies with cardiomyopathy

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