Most common symptoms of cushing syndrome
What are the most common clinical features of cushing syndrome
Cushing syndrome is characterized by progressive physical changes, which are often best appreciated in serial photographs:
• Central (truncal) obesity
• Moon facies
• Dorsocervical fat pad (buffalo hump)
• Purple abdominal striae may be the most specific physical sign if >2.5 cm wide
• Plethora
• Ecchymoses
• Hypertrichosis
• Muscle weakness and atrophy, which are typically noted when climbing stairs or arising from a chair.
Other features of Cushing syndrome include emotional and cognitive changes, menstrual irregularity, glucose intolerance, and hypertension. Growth restriction is universal in children with Cushing syndrome.
