Indications for a renal biopsy in SLE

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What are the indications for a renal biopsy in an SLE patient?

• Increasing serum creatinine without a compelling alternative cause (e.g., hypovolemia and medication)

• Confirmed proteinuria of ≥ 1 g/24 hours

• Proteinuria ≥ 0.5 g/day plus hematuria or cellular casts

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