Hypoxic Ischemic Encephalopathy

6 Interesting Facts of Hypoxic Ischemic Encephalopathy

1. Intracranial pathology such as hypoxic-ischemic encephalopathy and intracranial hemorrhage may present similarly with central nervous system irritability and seizures 
2. Underlying causes of neonatal intracranial hemorrhage are diverse (eg, stroke, prematurity, trauma, bleeding diathesis, vascular malformations) 
3. Cause of hypoxic-ischemic encephalopathy is compromised blood or oxygen supply during pregnancy and/or intrapartum period (eg, placental abruption, tight nuchal cord, cord prolapse, amniotic fluid embolism) 
4. Neonates with hypoxic-ischemic encephalopathy often present with significant metabolic acidosis and multisystem organ failure 
5. Focal neurologic findings suggest intracranial insult such as hypoxic-ischemic encephalopathy and intracranial hemorrhage 
6. Differentiate and diagnose intracranial pathology with imaging (eg, ultrasonography, MRI)