How is Minimal change disease diagnosed

How is Minimal change disease diagnosed?

Minimal change disease presents with nephrotic syndrome.

However, the child who presents with typical features (see question 1) of nephrotic syndrome is presumed to have Minimal change disease and does not undergo a kidney biopsy unless there are unusual factors such as resistance to prednisone therapy, hypertension, decreased kidney function, or hypocomplementemia.

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