Symptoms of Minimal change disease
What is the typical clinical presentation of Minimal change disease?
Patients with Minimal change disease typically present with mild to severe edema.
Because the onset with periorbital edema commonly follows an upper respiratory infection in young children, nephrotic syndrome may sometimes be confused with an allergic reaction until a more thorough evaluation is performed.
In the youngest children, there is a 2:1 male to female prevalence, but by adolescence and beyond males and females are equally affected.
Other symptoms can include abdominal pain, diarrhea, poor appetite, and decreased urine output.
Rarely, a patient may present with sepsis.