How is hypoglycemia diagnosed in patients with and without diabetes

How is hypoglycemia diagnosed in patients with and without diabetes? 

Hypoglycemia is defined by a blood glucose value of less than 70 mg/dL in patients with diabetes. Insulin therapy and other antidiabetic medications that cause low blood sugars are the leading culprits. 

In patients without diabetes, the following hypoglycemia triad (known as Whipple’s triad) should be established:

  • • Symptoms of hypoglycemia (e.g., sweating, cognitive impairment, dizziness, palpitations)
  • • Measured low blood glucose (< 70 mg/dL) at the time of hypoglycemic symptoms
  • • Resolution of symptoms with food intake (i.e., glucose)

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