- A rare inborn error of metabolism characterized by a deficiency in erythrocyte catalase, an enzyme responsible for the breakdown of hydrogen peroxide.
- The disorder is usually asymptomatic but may be associated with oral ulcerations and gangrene, or diabetes mellitus and atherosclerosis in certain populations.
How common is Acatalasemia?
Age of Onset
What are the symptoms of Acatalasemia?
Very Common Symptoms
Reduced catalase activity
- Gingival bleeding
- Microcytic anemia
- Old-aged sensorineural hearing impairment
- Severe periodontitis
- Type II diabetes mellitus
- Neoplasm of the larynx
- Premature loss of permanent teeth
- Type I diabetes mellitus