How does osteoporosis differ from osteopenia osteomalacia and osteosclerosis

How does osteoporosis differ from osteopenia osteomalacia and osteosclerosis

  • • Osteoporosis is characterized by diminished bone density with otherwise normal bone architecture. The main radiographic finding is cortical thinning. Loss of bony trabeculae may also be seen.
  • • Osteomalacia is characterized by normal bone density in the setting of abnormal quality of the bone, leading to excess non-mineralized osteoid. In a growing child, this is referred to as rickets.
  • • Osteopenia is characterized by diffusely increased lucency of bone as seen on radiography or computed tomography (CT). It is sometimes difficult to distinguish between osteoporosis and osteomalacia radiographically.
  • • Osteosclerosis is diffusely increased density of bone as seen on radiography or CT.
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