How does osteoporosis differ in men?
Approximately 1 to 2 million men in the United States have osteoporosis. The diagnostic criteria are the same in men as in women (fragility fracture, T-score <–2.5, FRAX risk scores). Nearly two-thirds of osteoporotic men have an identifiable secondary cause of bone loss, most often alcohol abuse, GC use, and hypogonadism, including gonadotropin-releasing hormone analog use for prostate cancer. Treatment is generally the same in men as in women, although testosterone replacement in hypogonadal men is an effective adjunctive strategy.