Does calcium or vitamin D supplementation promote vascular calcification or coronary artery disease

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Does calcium or vitamin D supplementation promote vascular calcification or coronary artery disease (CAD)?

The suggestion that calcium and/or vitamin D supplementation promotes calcification of coronary arteries came from several early, small studies that gained significant attention from the lay press. However, subsequent large reviews and metaanalyses clearly demonstrated that the existing published evidence does not support the hypothesis that calcium and/or vitamin D supplementation in the recommended doses increases the risk of CAD or CAD mortality. As stated above, however, excessive doses should be avoided especially in patients with renal insufficiency.

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