Differential Diagnosis of Salivary Gland Enlargement

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Differential Diagnosis of Salivary Gland Enlargement

Usually unilateral
Bacterial infectionChronic sialadenitisLymphoma
ObstructionPrimary salivary gland neoplasms
Usually bilateral (asymmetric)
Granulomatous diseasesHIV/Diffuse infiltrative lymphocytosis syndrome (HIV-Associated Rheumatic Syndromes)IgG4-related disease (may be massive)
Recurrent parotitis of childhoodViruses (mumps, cytomegalovirus, influenzae, coxsackie A)
Bilateral (symmetric)
AcromegalyAlcoholismAnorexia/bulimia
Chronic pancreatitisDiabetes mellitusGonadal hypofunction
Hepatitis cirrhosisHyperlipoproteinemiaIdiopathic

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