Contraindications of 90 Y radioembolization

Contraindications of 90 Y radioembolization

• Uncorrectable coagulopathy

• Severe anaphylactic or anaphylactoid contrast reaction

• Severe liver or renal dysfunction

• Lung or gastrointestinal (GI) shunts that cannot be corrected

• Untreated varices at high risk of bleeding

• Bilirubin greater than 2 mg/dL in the absence of a reversible cause

• Greater than 70% tumor replacement of liver unless synthetic function (prothrombin time and albumin) is maintained

• Prior radiation therapy to the liver or upper abdomen that included a significant volume of the liver

• Systemic chemotherapy agents in the preceding 4 weeks not known to be used safely concurrently with radioembolization

• Granulocyte count less than 1.5 × 10 /L


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