Contraindications to thrombolysis

Contraindications to thrombolysis

  • • Absolute contraindications include active internal bleeding, known intracranial pathology, stroke within the past 6 months, craniotomy in the past 2 months, irreversible limb ischemia, and infected bypass graft.
  • • Relative contraindications include uncontrollable hypertension, history of gastrointestinal bleeding, bacterial endocarditis, diabetic retinopathy, coagulopathy, pregnancy, recent major surgery, recent major trauma, and recent cardiopulmonary resuscitation.

In patients with relative contraindications, it is imperative to analyze the potential risk-to-benefit ratio carefully in each case.


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