What is SIRT or radioembolization?
SIRT, or radioembolization, is a transarterial method for treating hepatic malignancies that involves selective intraarterial delivery of microspheres loaded with a radioisotope. It is a form of intraarterial brachytherapy.
The primary mode of action is the emission of radiation and the second mode of action is the embolization of the vasculature. Yttrium-90 ( 90 Y) is the most common radioisotope used for radioembolization.
It is a beta emitter, has a mean tissue penetration of 2.5 mm and a maximum penetration of 11 mm, and a half-life of 64.2 hours.