Conditions where Blood Brain Barrier compromised

Conditions where Blood Brain Barrier compromised

Under what conditions is the integrity of the BBB compromised?

  • Autoimmune inflammation or infection (e.g., multiple sclerosis)
  • Osmotic injury (e.g., rapid correction of hyponatremia)
  • Vascular overpressure (e.g., malignant hypertension, reperfusion after ischemia)
  • Neovascularization (e.g., cancer)
  • Neuronal hyperexcitability (e.g., seizures)
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